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Technology

A Video Journey Into Nanotechnology - An animated video describing the promise of nanotechnology in the diagnosis, prevention and treatment of diseases, including cancer. To view this video you will need Windows Media Player or Apple Quicktime installed on your computer, which you can download for free for either a PC or a Macintosh. A text version of this video is also available. (National Cancer Institute)
http://nano.cancer.gov/resource_center/video_journey.asp
Equal Arm Analytical Balances (Exhibit) - Online exhibit about equal arm analytic balances - instruments, designed on a "seesaw" principle, to measure mass precisely by placing a sample in one pan and known weight in an opposing pan until an equilibrium is established. (DeWitt Stetten, Jr., Museum of Medical Research) (Office of NIH History)
http://history.nih.gov/exhibits/balances/
Exploring Nanotechnology in Cancer - A primer on nanotechnology and it promise to offer unprecedented and paradigm-changing opportunities to study and interact with normal and cancer cells in real time, at the molecular and cellular scales, and during the earliest stages of the cancer process. (National Cancer Institute)
http://nano.cancer.gov/nanotech_why_in_cancer.asp
Measuring Fluorescence for Medical Research: The AMINCO-Bowman Spectrophotofluorometer (Exhibit) - An online exhibit about Dr. Robert Bowman who developed a sensitive instrument called the spectrophotofluorometer, or "SPF", that allowed scientists to use fluorescence as a way to identify and measure tiny amounts of substances in the body. This exhibit explores the instrument and its use in scientific studies ranging from anti-depressant medication to AIDS research and the Human Genome Project. (DeWitt Stetten, Jr., Museum of Medical Research) (Office of NIH History)
http://history.nih.gov/exhibits/bowman/
Medical Instruments (Exhibit) - A cross section of precision instruments used between 1945 and 1965 at the National Institutes of Health. (DeWitt Stetten, Jr., Museum of Medical Research) (Office of NIH History)
http://history.nih.gov/exhibits/galleries/instrument/
Nanoparticles (Animation) - Nanoparticulate technology can prove to be very useful in cancer therapy allowing for effective and targeted drug delivery by overcoming the many biological, biophysical and biomedical barriers that the body stages against a standard intervention such as the administration of drugs or contrast agents. (National Cancer Institute)
http://nano.cancer.gov/nanotech_nanoparticles.asp
Nanoscale Cantilevers (Animation) - Nanoscale cantilevers – microscopic, flexible beams resembling a row of diving boards – are built using semiconductor lithographic techniques. These can be coated with molecules capable of binding specific substrates—DNA complementary to a specific gene sequence, for example. Such micron-sized devices, comprising many nanometer-sized cantilevers, can detect single molecules of DNA or protein. (National Cancer Institute)
http://nano.cancer.gov/nanotech_cantilevers.asp
Nanoshells (Animation) - Nanoshells have a core of silica and a metallic outer layer. Because of their size, they will preferentially concentrate in cancer lesion sites. This physical selectivity occurs through a phenomenon called enhanced permeation retention (EPR). (National Cancer Institute)
http://nano.cancer.gov/nanotech_nanoshells.asp
Nanowires (Animation) - Nanowires are man-made constructs made with carbon, silicon and other materials that have the capability to monitor the complexity of biological phenomenon and relay the information, as it is monitored, to the medical care provider. (National Cancer Institute)
http://nano.cancer.gov/nanotech_nanowires.asp
NIH Image - NIH Image is a public domain image processing and analysis program for the Macintosh. It was developed at the Research Services Branch (RSB) of the National Institute of Mental Health (NIMH), part of the National Institutes of Health (NIH). A free PC version of Image, called Scion Image for Windows, is available from Scion Corporation. There is also Image/J, a Java program inspired by Image that "runs anywhere". (National Institute of Mental Health)
http://rsb.info.nih.gov/nih-image/

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