Publications and Presentations
Publications, Presentations and Reports
The Early Detection Research Network (ppt, 1.2mb)
Measuring EDRN Success (ppt, 689kb)
Feburary 5, 2003: EDRN develops informatics prototypes for accessing biorepository across EDRN Centers, article, Journal of the National Cancer Institute (Access to this article requires subscription to the JNCI Spectrum)
Early Detection Implementation Group (pdf, 1.01mb)
Extraordinary Opportunities for Early Cancer Detection and Risk Assessment Research
EDRN publications
October, 2000: "Initial Report of the Early Detection Research Network: Advancing Translational Research to Identify Early Cancer and Cancer Risk" (pdf, 324kb)
Workshop Reports
HUPO Presentations
Reproducibility of 2D gel-based proteomics experiments
Biomarkers and FDA Regulation of In Vitro Diagnositc Devices
Validation in the eyes of a clinical scientist
Development of Molecular In Vitro Diagnostics for the Early Detection of Cancer
EDRN Progress Reports
Journal Articles
2008
Block, T.M., Marrero, J., Gish, R., Sherman, M., London, W.T., Srivastava, S., and Wagner, P.D.: The Degree of Readiness of Selected Biomarkers for the Early Detection of Hepatocellular Carcinoma: Notes from a Recent Workshop. Cancer Biomarkers 2008; 4:19-33, 2008.
Maggrah, A., Maragh, S., Maki1, J., Reguly B., Wittock, R., Robinson, K., Wagner, P.D., Thayer, R.E., Gehman, K., Gehman, T., Srivastava, S., Ngom, A., Dakubo, G.D., Jakupciak, J.P., and Par, R.L.: Facile whole mitochondrial genome sequencing from nipple aspirate fluid using MitoChip v2.0. BMC Cancer 2008; 8:95.
Maki, J., Robinson, K., Reguly, B., Alexander, J., Wittock, R., Aguirre, A., Diamandis, A.P., Escott, N., Skehan, A., Prowse, O, Thayer, R.E., Froberg, M.K., Wilson, M.J., Maragh, S., Jakupciak, J.P., Wagner, P.D., Srivastava, S., Dakubo, G.D., and. Parr, R.L.: Mitochondrial genome deletion aids in the identification of both false and true negative prostate needle core biopsies. Am J Clin Pathol 2008; 129: 57-66.
Maragh S, Wagner, P.D., Srivastava, S.. Jakupciak, J., Catherine D. O’Connell: Multiple Strand Displacement Amplification of Mitochondrial DNA from Clinical Samples. BMC Med Genet 2008; 9:7.
McLerran D, Grizzle WE, Feng Z, Bigbee WL, Banez LL, Cazares LH, et al. Analytical validation of serum proteomic profiling for diagnosis of prostate cancer: sources of sample bias. Clin Chem 2008;54:44-52.
McLerran D, Grizzle WE, Feng Z, Thompson IM, Bigbee WL, Cazares LH, et al. SELDI-TOF MS whole serum proteomic profiling with IMAC surface does not reliably detect prostate cancer. Clin Chem 2008;54:53-60.
Seurynck-Servoss SL, Baird CL, Miller KD, Pefaur NB, Gonzalez RM, Apiyo DO,
Engelmann HE, Srivastava S, Kagan J, Rodland KD, Zangar RC. Immobilization strategies for single-chain antibody microarrays. Proteomics 2008;8:2199-2210.
Srivastava, S. and Krueger, K.E. Diagnostics other than blood. In Saliva Diagnostics, (Wong, D. ed.). Ames, Iowa: Blackwell Publishing; 2008. (in press).
Sokoll LJ, Wang Y, Feng Z, Kagan J, Partin AW, Sanda MG, et al. [-2]Proenzyme Prostate Specific Antigen for Prostate Cancer Detection: A National Cancer Institute Early Detection Research Network Validation Study. J Urol 2008; (in press).
Xiao, Y., Gao, X., Gannot, G, Emmert-Buck, M. R, Srivastava, S., Wagner P.D., Amos M.D., and Barker, P.E.: Quantitation of HER2 and telomerase biomarkers in solid tumors with IgY antibodies and nanocrystal detection. Int J Cancer 2008; 122: 2178-2186.
2007
Kagan J, Srivastava S, Barker PE, Belinsky SA, Cairns P. Towards clinical application of methylated DNA sequences as cancer biomarkers: A joint National Cancer Institute’s Early Detection Research Network and National Institute of Standards and Technology workshop on standards, methods, assays, reagents, and tools. Cancer Res 2007; 67: 4545-4549.
Srivastava S, Wagner PD: Risk-based and Diagnostics-linked personalized medicine for cancer. Person Med 2007;4:33-43.
2006
Barker PE, Wagner PD, Stein SE, Bunk DM, Srivastava S, Omenn GS. Standards for plasma and serum proteomics in early cancer detection: A needs assessment report from the NIST-NCI SMART Workshop, August 18-19, 2005. Clinical Chem 2006;52:1669-72.
Krueger KE. The potential of serum proteomics for detection of cancer: Promise or only hope? Onkologie 2006;29:498-9.
Krueger KE, Srivastava S. Posttranslational protein modifications: Current implications for cancer detection, prevention, and therapeutics. Mol Cell Proteomics 2006;5:1799-810.
Krueger KE, Srivastava S. Biomarkers. In: Rom WN editor. Environmental and Occupational Medicine, 4th edition. Philadelphia (PA): Lippincott Williams & Wilkins; 2006. p. 109-20.
Maruvada P, Srivastava S. Joint National Cancer Institute-Food and Drug Administration workshop on research strategies, study designs, and statistical approaches to biomarker validation for cancer diagnosis and detection. Cancer Epidemiol Biomarkers Prev 2006;15 :1078-82.
McGruder BM, Atha DH, Wang W, Huppi K, Wei WQ, Abnet CC, et al. Real-time telomerase assay of less-invasively collected esophageal cell samples. Cancer Lett 2006;244:91-100.
Srivastava S. Molecular screening of cancer: the future is here. Mol Diagn Ther 2006;10:221-30.
2005
Dixit R, Srivastava S. Cancer Biomakers. Preface Cancer Biomarkers 2005;1:3-4.
Jakupciak JP, Barker PE, Wang W, Srivastava S, Atha DH. Preparation and characterization of candidate reference materials for telomerase assays. Clin Chem 2005;51:1443-50.
Jakupciak JP, Wang W, Markowitz ME, Ally D, Coble M, Srivastava S, et al. Mitochondrial DNA as a cancer biomarker. J Mol Diagn 2005;7:258-67.
Manne U, Srivastava RG, Srivastava S. Recent advances in biomarkers for cancer diagnosis and treatment. Drug Discov Today 2005;10:965-76.
Maruvada P, Wang W, Wagner PD, Srivastava S. Biomarkers in molecular medicine: cancer detection and diagnosis. Biotechniques 2005;April Suppl:9-15.
Srivastava S. Cancer biomarkers: an emerging means of detecting, diagnosing and treating cancer. Dis Markers 2005;21:1-2.
Srivastava S, Srivastava RG. Proteomics in the forefront of cancer biomarker discovery. J Proteome Res 2005;4:1098-103.
Srivastava S, Verma M, Gopal-Srivastava R. Proteomic maps of the cancer-associated infectious agents. J Proteome Res 2005;4:1171-80.
Wagner PD, Srivastava S: The Promise of Proteomics: Biology, Applications and Challenge. In: Srivastava S, editor. Informatics and Proteomics. CRC Press. 2005; p. 1-17.
2004-2000
Atha DH, Miller K, Sanow AD, Xu J, Hess JL, Wu OC, et al. High-throughput analysis of telomerase by capillary electrophoresis. Electrophoresis 2003; 24:109-14.
Barker PE, Wang W, Wagner PD, Pinsky P. Inter-rater agreement on chromosome 5 breakage in FISH-based mutagen sensitivity assays (MSAs). Mutat Res 2004; 562:133-42.
Grizzle WE, Adam B-L, Bigbee WL, Conrads TP, Carroll C, Feng Z, et al. Serum protein expression profiling for cancer detection: validation of a SELDI-based approach for prostate cancer. Dis Markers 2003-2004; 19:185-95.
Grizzle WE, Semmes OJ, Basler J, Izbicka E, Feng Z, Kagan J, et al. The early detection research network surface-enhanced laser desorption and ionization prostate cancer detection study: A study in biomarker validation in genitourinary oncology. Urol Oncol 2004; 22:337-43.
Habis AH, Vernon SD, Lee DR, Verma M, Unger ER. Molecular quality of exfoliated cervical cells: implications for molecular epidemiology and biomarker discovery. Cancer Epidemiol Biomarkers Prev 2004; 13:492-6.
Jakupciak JP, Wang W, Barker PE, Srivastava S, Atha DH. Analytical validation of telomerase activity for cancer early detection: TRAP/PCR-CE and hTERT mRNA quantification assay for high-throughput screening of tumor cells. J Mol Diagn 2004; 6:157-65.
Maruvada P, Srivastava S. Biomarkers for cancer diagnosis: implications for nutritional research. J Nutr 2004; 134:1640S-45S.
Rajeevan MS, Dimulescu IM, Vernon SD, Verma M, Unger ER. Global amplification of sense RNA: a novel method to replicate and archive mRNA for gene expression analysis. Genomics 2003; 82:491-7.
Ravichandran R, Vasquez GB, Srivastava S, Verma M, Petricoin E, Lubell J, et al. Data standards for proteomics: Mitochondrial two-dimensional polyacrylamide gel electrophoresis data as a model system. Mitochondrion 2004; 3:327-36.
Verma M. Viral genes and methylation. Ann NY Acad Sci 2003; 983:1-11.
Verma M, Dunn BD, Ross S, Jain P, Wang W, Hayes R, Umar A. Proceedings of the workshop on epigenetics in cancer prevention: early detection and risk assessment. Ann NY Acad Sci. 2003; 983:298-319.
Verma M, Maruvada P, Srivastava S. Current approaches in mitochondrial proteomics. MitoMatters 2004; 3(3-5).
Verma M, Maruvada P, Srivastava S. Epigenetics and cancer. Crit Rev Clin Lab Sci 2004;41:585-607.
Wagner PD, Maruvada P, Srivastava S. Molecular diagnostics: a new frontier in cancer prevention. Expert Rev Mol Diagn 2004;4:503-11.
