8:20
- 8:30 Welcome
Daniel Camerini-Otero, NIDDK
Michael Gottesman, Deputy Director, NIH |
8:30
- 10:30 Modeling Biological Systems: Network Structure,
Noise and Flux
Moderator: Ronald Germain, NIAID |
Bernhard
Palsson
University of California, San Diego |
Developing
Mechanistic Genotype-Phenotype Relationships: the Case
of Microbial Metabolism |
Luis
A. Nunes Amaral
Northwestern University |
Cartographic
Methods for Systems Biology |
Johan
Paulsson
Harvard Medical School |
Physical
Limits on Noise Suppression |
Harley
McAdams
Stanford University |
Architecture
and Inherent Robustness of a Bacterial Cell Cycle Control
System |
| 10:30
- 11:00 Break |
11:00
- 12:30 Genetic Networks and Regulatory Controls
Moderator: Teresa Przytycka, NCBI |
Martha
Bulyk
Harvard Medical School |
Genomic
Analysis of Transcription Factors and Cis Regulatory Elements:
Regulatory Codes in DNA |
Saeed
Tavazoie
Princeton University |
Predictive
Behavior Within Microbial Genetic Networks |
David
Gifford
Massachusetts Institutes of Technology |
Building
Successful Collaborations for Systems Biology |
| 12:30
- 1:30 Lunch |
1:30
- 3:30 Integrative Systems Biology
Moderator: Gisela Storz, NICHD |
Lucy
Shapiro
Stanford University |
Integration
of Dynamic Protein Localization, Proteolysis and Phospho-signaling
Drives Transcriptional Cell Cycle Circuitry |
Andrew
Emili
University of Toronto |
Uncovering
Functional Relationships in E. coli on a Genome-Wide Scale
using Proteomics, Comparative Genomics and Synthetic Genetic
Arrays |
David
Botstein
Princeton University |
Coordination
of Growth Rate, Cell Cycle, Stress Response and Metabolic
Activity in Yeast |
Aimee
Dudley
Institute for Systems Biology |
Integrating
Spatial Dynamics and Genetic Variation into Systems Biology |
| 3:30
- 4:00 Break |
4:00
- 6:00 Systems Biology of Disease
Moderator: Alan Michelson, NHLBI |
Daphne
Koller
Stanford University |
Individual
Genetic Variation and Regulatory Networks |
Edward
Marcotte
University of Texas, Austin |
Steps
Toward Directed Identification of Disease Genes: Predicting
the Consequences of Genetic Perturbations |
Andrea
Califano
Columbia University Medical Center |
Cancer
Systems Biology Comes of Age: Using Context-Specific Molecular
Interaction Networks to Dissect Physiological and Pathological
Phenotypes in Human Cells |
Stuart
Orkin
Harvard Medical School |
Control
of Pluripotency |
6:00
- 6:10 Closing Remarks
David Levens, NCI |
