Multilevel Effects of Functional Loci in Complex Behavior |
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| Air date: | Monday, September 15, 2008, 12:00:00 PM |
| Category: | Neuroscience |
| Description: | Dr. Goldman's lab generates the clinical dataset collections and collaborations, and encompasses the DNA/Data core, ongoing human research protocols (COMBINE, Ten Tribes Study, Alaska Native Alcohol treatment pharmacogenetics), large scale SNP detection and genotyping, in vitro and in vivo functional analyses of receptor variants, and linkage studies of markers and candidate alleles.
Selected Publications: Jon-Kar Zubieta, Mary M. Heitzeg, Yolanda R. Smith, Joshua A. Bueller, Ke Xu, Yanjun Xu, Robert A. Koeppe, Christian S. Stohler, David Goldman: COMT val158met Genotype Affects mu-Opioid Neurotransmitter Responses to a Pain Stressor. Science 2003;299:1240-43. Michael F. Egan, Terry E. Goldberg, Bhaskar S. Kolachana, Joseph H. Callicott, Chiara M. Mazzanti, Richard E. Straub, David Goldman, and Daniel R. Weinberger: Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci 2001;98(12):6917–22. Ke Xu, Dirk Lichtermann, Robert H. Lipsky, Petra Franke, Xiehe Liu, Ying Hu, Liping Cao, Sibylle G. Schwab, Dieter B. Wildenauer, Claiton HD Bau, Erica Ferro, Will Astor, Thembi Finch, Jeanietta Terry, Julie Taubman, Wolfgang Maier, David Goldman: Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations. Arch Gen Psychiatry 2004;61(6):597-606. Ahmad R. Hariri, Venkata S. Mattay, Alessandro Tessitore, Bhaskar Kolachana, Francesco Fera, David Goldman, Michael F. Egan, Daniel R. Weinberger: Serotonin transporter genetic variation and the response of the human amygdala. Science 2002;297(5580):400-3. For more information see our website - NIH Neuroscience Seminar Series |
| Author: | David Goldman, M.D., Lab of Neurogenetics NIAAA/NIH |
| Runtime: | 75 minutes |
| Download: | Download
Video How to download a Videocast |
| CIT File ID: | 14639 |
| CIT Live ID: | 7122 |
| Permanent link: | http://videocast.nih.gov/launch.asp?14639 |
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| Description | Runtime | Description | Runtime | |||
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Enhanced Audio Podcast | 59:40 |
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Enhanced Video Podcast | 59:40 | |