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Disease/Syndrome Shigellosis
Category Infection, Travel
Acute/Chronic Acute-Moderate
Synonyms Bacillary dysentery; infection by Shigella dysenteriae, S. flexnerii, S. sonnei, and S. boydii;
Biomedical References Search PubMed
Comments In typical cases, patients have fever, abdominal cramping, and voluminous diarrhea initially, followed by frequent stools of smaller volume. Then within another day or two, patients have bloody, mucoid stools and rectal urgency. In retrospective analyses, 1/3 of patients with shigellosis have fever, 2/5 have grossly bloody stools. An increased percentage of immature neutrophils in the CBC differential (shift to the left) is a typical finding in bacillary dysentery. [PPID, p. 2657-8] This is usually a self-limited infection lasting up to a week. Complications include Reiter's syndrome, toxic megacolon, intestinal perforation, and hemolytic-uremic syndrome. Febrile convulsions may be seen in children. Outbreaks are seen in crowded institutional settings where residents have poor personal hygiene and also among men who have sex with men. Daycare attendees have increased risk for infection. Flies may transmit infection from latrines. [CCDM, p. 487-91] Shigella bacteria can cause conjunctivitis and keratitis. [Guerrant, p. 1575] The gastroenteritis caused by enteroinvasive strains of E. coli (EIEC) is similar to shigellosis. About 1% to 5% of the cases of diarrhea in developing countries are caused by EIEC. [CCDM, p. 166-7]
Latency/Incubation 1-3 days; range of 12-96 hours;
Diagnostic Culture
ICD-9 Code 004
Effective Antimicrobics Yes
Reference Link CDC - Shigellosis
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Last updated: September, 2008