Paul M Hwang's Web Page

(Last updated by Paul Hwang on 11/26/2007 at 4:24 PM.)

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Publications

1 Fields J, Hanisch JJ, Choi JW, Hwang P
How does p53 regulate mitochondrial respiration?
IUBMB Life 59(10): 682-4, 2007. [Text Abstract on PubMed]
2 Liu H, Fergusson MM, Castilho RM, Liu J, Cao L, Chen J, Malide D, Rovira II, Schimel D, Kuo CJ, Gutkind JS, Hwang PM, Finkel
Augmented Wnt signaling in a mammalian model of accelerated aging.
Science 317(5839): 803-6, 2007. [Text Abstract on PubMed]
3 Ma W, Sung HJ, Park JY, Matoba S, Hwang P
A pivotal role for p53: balancing aerobic respiration and glycolysis.
J Bioenerg Biomembr 39(3): 243-6, 2007. [Text Abstract on PubMed]
4 Matsumoto T, Hwang P
Resizing the genomic regulation of restenosis.
Circ Res 100(11): 1537-9, 2007. [Text Abstract on PubMed]
5 Das H, Kumar A, Lin Z, Patino WD, Hwang PM, Feinberg MW, Majumder PK, Jain M
Kruppel-like factor 2 (KLF2) regulates proinflammatory activation of monocytes.
Proc Natl Acad Sci U S A 103(17): 6653-8, 2006. [Text Abstract on PubMed]
6 Kang JG, Patino WD, Matoba S, Hwang P
Genomic analysis of circulating cells: a window into atherosclerosis.
Trends Cardiovasc Med 16(5): 163-8, 2006. [Text Abstract on PubMed]
7 Matoba S, Kang JG, Patino WD, Wragg A, Boehm M, Gavrilova O, Hurley PJ, Bunz F, Hwang P
p53 regulates mitochondrial respiration.
Science 312(5780): 1650-3, 2006. [Text Abstract on PubMed]
8 Patino WD, Kang JG, Matoba S, Mian OY, Gochuico BR, Hwang P
Atherosclerotic plaque macrophage transcriptional regulators are expressed in blood and modulated by tristetraprolin.
Circ Res 98(10): 1282-9, 2006. [Text Abstract on PubMed]
9 Matoba S, Hwang PM, Nguyen T, Shizukuda Y.
Evaluation of pulsed Doppler tissue velocity imaging for assessing systolic function of murine global heart failure.
J Am Soc Echocardiogr 18(2): 148-54, 2005. [Text Abstract on PubMed]
10 Patino WD, Mian OY, Kang JG, Matoba S, Bartlett LD, Holbrook B, Trout HH, Kozloff L, Hwang PM.
Circulating transcriptome reveals markers of atherosclerosis.
Proc Natl Acad Sci U S A 102(9): 3423-8, 2005. [Text Abstract on PubMed]
11 Shizukuda Y, Matoba S, Mian OY, Nguyen T, Hwang PM.
Targeted disruption of p53 attenuates doxorubicin-induced cardiac toxicity in mice.
Mol Cell Biochem 273(1-2): 25-32, 2005. [Text Abstract on PubMed]
12 Patino WD, Mian OY, Shizukuda Y, Hwang PM.
Current and future applications of SAGE to cardiovascular medicine.
Trends Cardiovasc Med 13(4): 163-8, 2003. [Text Abstract on PubMed]
13 Patino WD, Mian OY, Hwang PM.
Serial analysis of gene expression: technical considerations and applications to cardiovascular biology.
Circ Res 91(7): 565-9, 2002. [Text Abstract on PubMed]
14 Wu SC, Yeung JC, Hwang PM, Wong SL.
Design, production, and characterization of an engineered biotin ligase (BirA) and its application for affinity purification of staphylokinase produced from Bacillus subtilis via secretion.
Protein Expr Purif 24(3): 357-65, 2002. [Text Abstract on PubMed]
15 Hwang PM, Bunz F, Yu J, Rago C, Chan TA, Murphy MP, Kelso GF, Smith RA, Kinzler KW, Vogelstein B.
Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells.
Nat Med 7(10): 1111-7, 2001. [Text Abstract on PubMed]
16 Yu J, Zhang L, Hwang PM, Kinzler KW, Vogelstein B.
PUMA induces the rapid apoptosis of colorectal cancer cells.
Mol Cell 7(3): 673-82, 2001. [Text Abstract on PubMed]
17 Chan TA, Hwang PM, Hermeking H, Kinzler KW, Vogelstein B.
Cooperative effects of genes controlling the G(2)/M checkpoint.
Genes Dev 14(13): 1584-8, 2000. [Text Abstract on PubMed]
18 Bunz F, Hwang PM, Torrance C, Waldman T, Zhang Y, Dillehay L, Williams J, Lengauer C, Kinzler KW, Vogelstein B.
Disruption of p53 in human cancer cells alters the responses to therapeutic agents.
J Clin Invest 104(3): 263-9, 1999. [Text Abstract on PubMed]
19 Velculescu VE, Madden SL, Zhang L, Lash AE, Yu J, Rago C, Lal A, Wang CJ, Beaudry GA, Ciriello KM, Cook BP, Dufault MR, Ferguson AT, Gao Y, He TC, Hermeking H, Hiraldo SK, Hwang PM, Lopez MA, Luderer HF, Mathews B, Petroziello JM, Polyak K, Zawel L, Kinzler KW.
Analysis of human transcriptomes.
Nat Genet 23(4): 387-8, 1999. [Text Abstract on PubMed]
20 Yu J, Zhang L, Hwang PM, Rago C, Kinzler KW, Vogelstein B.
Identification and classification of p53-regulated genes.
Proc Natl Acad Sci U S A 96(25): 14517-22, 1999. [Text Abstract on PubMed]
21 Tanaka K, Pracyk JB, Takeda K, Yu ZX, Ferrans VJ, Deshpande SS, Ozaki M, Hwang PM, Lowenstein CJ, Irani K, Finkel T.
Expression of Id1 results in apoptosis of cardiac myocytes through a redox-dependent mechanism.
J Biol Chem 273(40): 25922-8, 1998. [Text Abstract on PubMed]
22 Chao DS, Hwang PM, Huang F, Bredt DS.
Localization of neuronal nitric oxide synthase.
Methods Enzymol 268: 488-96, 1996. [Text Abstract on PubMed]
23 Fotuhi M, Sharp AH, Glatt CE, Hwang PM, von Krosigk M, Snyder SH, Dawson TM.
Differential localization of phosphoinositide-linked metabotropic glutamate receptor (mGluR1) and the inositol 1,4,5-trisphosphate receptor in rat brain.
J Neurosci 13(5): 2001-12, 1993. [Text Abstract on PubMed]
24 Hwang PM, Cunningham AM, Peng YW, Snyder SH.
CDRK and DRK1 K+ channels have contrasting localizations in sensory systems.
Neuroscience 55(3): 613-20, 1993. [Text Abstract on PubMed]
25 Hwang PM, Fotuhi M, Bredt DS, Cunningham AM, Snyder SH.
Contrasting immunohistochemical localizations in rat brain of two novel K+ channels of the Shab subfamily.
J Neurosci 13(4): 1569-76, 1993. [Text Abstract on PubMed]
26 Hwang PM, Glatt CE, Bredt DS, Yellen G, Snyder SH.
A novel K+ channel with unique localizations in mammalian brain: molecular cloning and characterization.
Neuron 8(3): 473-81, 1992. [Text Abstract on PubMed]
27 Levin LR, Han PL, Hwang PM, Feinstein PG, Davis RL, Reed RR.
The Drosophila learning and memory gene rutabaga encodes a Ca2+/Calmodulin-responsive adenylyl cyclase.
Cell 68(3): 479-89, 1992. [Text Abstract on PubMed]
28 Bredt DS, Glatt CE, Hwang PM, Fotuhi M, Dawson TM, Snyder SH.
Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase.
Neuron 7(4): 615-24, 1991. [Text Abstract on PubMed]
29 Bredt DS, Hwang PM, Glatt CE, Lowenstein C, Reed RR, Snyder SH.
Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase.
Nature 351(6329): 714-8, 1991. [Text Abstract on PubMed]
30 Dawson TM, Bredt DS, Fotuhi M, Hwang PM, Snyder SH.
Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues.
Proc Natl Acad Sci U S A 88(17): 7797-801, 1991. [Text Abstract on PubMed]
31 Bredt DS, Hwang PM, Snyder SH.
Localization of nitric oxide synthase indicating a neural role for nitric oxide.
Nature 347(6295): 768-70, 1990. [Text Abstract on PubMed]
32 Hwang PM, Bredt DS, Snyder SH.
Autoradiographic imaging of phosphoinositide turnover in the brain.
Science 249(4970): 802-4, 1990. [Text Abstract on PubMed]
33 Hwang PM, Verma A, Bredt DS, Snyder SH.
Localization of phosphatidylinositol signaling components in rat taste cells: role in bitter taste transduction.
Proc Natl Acad Sci U S A 87(19): 7395-9, 1990. [Text Abstract on PubMed]
34 Snyder SH, Sklar PB, Hwang PM, Pevsner J.
Molecular mechanisms of olfaction.
Trends Neurosci 12(1): 35-8, 1989. [Text Abstract on PubMed]
35 Hwang PM, Byrne DH, Kitos PA.
Effects of molecular oxygen on chick limb bud chondrogenesis.
Differentiation 37(1): 14-9, 1988. [Text Abstract on PubMed]
36 Pevsner J, Hwang PM, Sklar PB, Venable JC, Snyder SH.
Odorant-binding protein and its mRNA are localized to lateral nasal gland implying a carrier function.
Proc Natl Acad Sci U S A 85(7): 2383-7, 1988. [Text Abstract on PubMed]