Robert S Adelstein's Web Page

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Publications

1 Conti MA, Adelstein R
Nonmuscle myosin II moves in new directions.
J Cell Sci 121(Pt 1): 11-8, 2008. [Text Abstract on PubMed]
2 Kim KY, Kawamoto S, Bao J, Sellers JR, Adelstein R
The B2 alternatively spliced isoform of nonmuscle myosin II-B lacks actin-activated MgATPase activity and in vitro motility.
Biochem Biophys Res Commun 369(1): 124-34, 2008. [Text Abstract on PubMed]
3 Bao J, Ma X, Liu C, Adelstein R
Replacement of nonmuscle myosin II-B with II-A rescues brain but not cardiac defects in mice.
J Biol Chem 282(30): 22102-11, 2007. [Text Abstract on PubMed]
4 Chen Z, Naveiras O, Balduini A, Mammoto A, Conti MA, Adelstein RS, Ingber D, Daley GQ, Shivdasani R
The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway.
Blood 110(1): 171-9, 2007. [Text Abstract on PubMed]
5 Even-Ram S, Doyle AD, Conti MA, Matsumoto K, Adelstein RS, Yamada K
Myosin IIA regulates cell motility and actomyosin-microtubule crosstalk.
Nat Cell Biol 9(3): 299-309, 2007. [Text Abstract on PubMed]
6 Ivanov AI, Bachar M, Babbin BA, Adelstein RS, Nusrat A, Parkos C
A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctions.
PLoS ONE 2(7): e658, 2007. [Text Abstract on PubMed]
7 Ma X, Bao J, Adelstein R
Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice.
Mol Biol Cell 18(6): 2305-12, 2007. [Text Abstract on PubMed]
8 Jana SS, Kawamoto S, Adelstein R
A specific isoform of nonmuscle myosin II-C is required for cytokinesis in a tumor cell line.
J Biol Chem 281(34): 24662-70, 2006. [Text Abstract on PubMed]
9 Ma X, Kawamoto S, Uribe J, Adelstein R
Function of the neuron-specific alternatively spliced isoforms of nonmuscle myosin II-B during mouse brain development.
Mol Biol Cell 17(5): 2138-49, 2006. [Text Abstract on PubMed]
10 Wu D, Asiedu M, Adelstein RS, Wei
A novel guanine nucleotide exchange factor MyoGEF is required for cytokinesis.
Cell Cycle 5(11): 1234-9, 2006. [Text Abstract on PubMed]
11 Bao J, Jana SS, Adelstein RS.
Vertebrate nonmuscle myosin II isoforms rescue small interfering RNA-induced defects in COS-7 cell cytokinesis.
J Biol Chem 280(20): 19594-9, 2005. [Text Abstract on PubMed]
12 Kim KY, Kovács M, Kawamoto S, Sellers JR, Adelstein RS.
Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C.
J Biol Chem 280(24): 22769-75, 2005. [Text Abstract on PubMed]
13 Meshel AS, Wei Q, Adelstein RS, Sheetz MP.
Basic mechanism of three-dimensional collagen fibre transport by fibroblasts.
Nat Cell Biol 7(2): 157-64, 2005. [Text Abstract on PubMed]
14 Conti MA, Even-Ram S, Liu C, Yamada KM, Adelstein RS.
Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice.
J Biol Chem 279(40): 41263-6, 2004. [Text Abstract on PubMed]
15 Golomb E, Ma X, Jana SS, Preston YA, Kawamoto S, Shoham NG, Goldin E, Conti MA, Sellers JR, Adelstein RS.
Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family.
J Biol Chem 279(4): 2800-8, 2004. [Text Abstract on PubMed]
16 Lo CM, Buxton DB, Chua GC, Dembo M, Adelstein RS, Wang YL.
Nonmuscle myosin IIb is involved in the guidance of fibroblast migration.
Mol Biol Cell 15(3): 982-9, 2004. [Text Abstract on PubMed]
17 Ma X, Kawamoto S, Hara Y, Adelstein RS.
A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons.
Mol Biol Cell 15(6): 2568-79, 2004. [Text Abstract on PubMed]
18 Buxton DB, Golomb E, Adelstein RS.
Induction of nonmuscle myosin heavy chain II-C by butyrate in RAW 264.7 mouse macrophages.
J Biol Chem 278(17): 15449-55, 2003. [Text Abstract on PubMed]
19 Obungu VH, Lee Burns A, Agarwal SK, Chandrasekharapa SC, Adelstein RS, Marx SJ.
Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain.
Oncogene 22(41): 6347-58, 2003. [Text Abstract on PubMed]
20 Takeda K, Kishi H, Ma X, Yu ZX, Adelstein RS.
Ablation and mutation of nonmuscle myosin heavy chain II-B results in a defect in cardiac myocyte cytokinesis.
Circ Res 93(4): 330-7, 2003. [Text Abstract on PubMed]
21 Wei Q, Adelstein RS.
Pitx2a expression alters actin-myosin cytoskeleton and migration of HeLa cells through Rho GTPase signaling.
Mol Biol Cell 13(2): 683-97, 2002. [Text Abstract on PubMed]
22 Bridgman PC, Dave S, Asnes CF, Tullio AN, Adelstein RS.
Myosin IIB is required for growth cone motility.
J Neurosci 21(16): 6159-69, 2001. [Text Abstract on PubMed]
23 Latham VM, Yu EH, Tullio AN, Adelstein RS, Singer RH.
A Rho-dependent signaling pathway operating through myosin localizes beta-actin mRNA in fibroblasts.
Curr Biol 11(13): 1010-6, 2001. [Text Abstract on PubMed]
24 Tullio AN, Bridgman PC, Tresser NJ, Chan CC, Conti MA, Adelstein RS, Hara Y.
Structural abnormalities develop in the brain after ablation of the gene encoding nonmuscle myosin II-B heavy chain.
J Comp Neurol 433(1): 62-74, 2001. [Text Abstract on PubMed]
25 Buxton DB, Adelstein RS.
Calcium-dependent threonine phosphorylation of nonmuscle myosin in stimulated RBL-2H3 mast cells.
J Biol Chem 275(44): 34772-9, 2000. [Text Abstract on PubMed]
26 Takeda K, Yu ZX, Qian S, Chin TK, Adelstein RS, Ferrans VJ.
Nonmuscle myosin II localizes to the Z-lines and intercalated discs of cardiac muscle and to the Z-lines of skeletal muscle.
Cell Motil Cytoskeleton 46(1): 59-68, 2000. [Text Abstract on PubMed]
27 Uren D, Hwang HK, Hara Y, Takeda K, Kawamoto S, Tullio AN, Yu ZX, Ferrans VJ, Tresser N, Grinberg A, Preston YA, Adelstein RS.
Gene dosage affects the cardiac and brain phenotype in nonmuscle myosin II-B-depleted mice.
J Clin Invest 105(5): 663-71, 2000. [Text Abstract on PubMed]
28 Wei Q, Adelstein RS.
Conditional expression of a truncated fragment of nonmuscle myosin II-A alters cell shape but not cytokinesis in HeLa cells.
Mol Biol Cell 11(10): 3617-27, 2000. [Text Abstract on PubMed]