Toren Finkel's Web Page

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Publications

1 Cron RQ, Bandyopadhyay R, Genin A, Brunner M, Kersh GJ, Yin J, Finkel TH, Crow MK.
Early Growth Response-1 Is Required for CD154 Transcription.
J Immunol 176(2): 811-818, 2006. [Text Abstract on PubMed]
2 Balaban RS, Nemoto S, Finkel T.
Mitochondria, oxidants, and aging.
Cell 120(4): 483-95, 2005. [Text Abstract on PubMed]
3 Finkel T.
Opinion: Radical medicine: treating ageing to cure disease.
Nat Rev Mol Cell Biol 6(12): 971-6, 2005. [Text Abstract on PubMed]
4 Khakoo AY, Finkel T.
Endothelial progenitor cells.
Annu Rev Med 56: 79-101, 2005. [Text Abstract on PubMed]
5 Kovacs B, Parry RV, Ma Z, Fan E, Shivers DK, Freiberg BA, Thomas AK, Rutherford R, Rumbley CA, Riley JL, Finkel TH.
Ligation of CD28 by Its Natural Ligand CD86 in the Absence of TCR Stimulation Induces Lipid Raft Polarization in Human CD4 T Cells.
J Immunol 175(12): 7848-7854, 2005. [Text Abstract on PubMed]
6 Liu H, Colavitti R, Rovira II, Finkel T.
Redox-dependent transcriptional regulation.
Circ Res 97(10): 967-74, 2005. [Text Abstract on PubMed]
7 Nemoto S, Fergusson MM, Finkel T.
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}.
J Biol Chem 280(16): 16456-60, 2005. [Text Abstract on PubMed]
8 Powell TM, Paul JD, Hill JM, Thompson M, Benjamin M, Rodrigo M, McCoy JP, Read EJ, Khuu HM, Leitman SF, Finkel T, Cannon RO.
Granulocyte colony-stimulating factor mobilizes functional endothelial progenitor cells in patients with coronary artery disease.
Arterioscler Thromb Vasc Biol 25(2): 296-301, 2005. [Text Abstract on PubMed]
9 Selliah N, Zhang M, Desimone D, Kim H, Brunner M, Ittenbach RF, Rui H, Cron RQ, Finkel TH.
The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells.
Virology: 2005. [Text Abstract on PubMed]
10 Shizukuda Y, Piekarz RL, Bates SE, Sachdev V, Finkel T, Rosing DR.
Effect of a histone deacetylase inhibitor on human cardiac mass.
Cardiovasc Drugs Ther 19(1): 89-90, 2005. [Text Abstract on PubMed]
11 Smith WW, Norton DD, Gorospe M, Jiang H, Nemoto S, Holbrook NJ, Finkel T, Kusiak JW.
Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.
J Cell Biol 169(2): 331-9, 2005. [Text Abstract on PubMed]
12 Feuerstein N, DeSimone DC, Eisenberg RA, Finkel TH.
Chronic graft-versus-host reaction is associated with a decrease in Ig light chain receptor editing in bone marrow self-reactive B cells.
Eur J Immunol 34(5): 1361-70, 2004. [Text Abstract on PubMed]
13 Finkel TH.
Tracking synapse-associated TCRs.
Nat Immunol 5(2): 117; author reply 117, 2004. [Text Abstract on PubMed]
14 Hill JM, Finkel T, Quyyumi AA.
Endothelial progenitor cells and endothelial dysfunction.
Vox Sang 87 Suppl 2: 31-7, 2004. [Text Abstract on PubMed]
15 Maus MV, Kovacs B, Kwok WW, Nepom GT, Schlienger K, Riley JL, Allman D, Finkel TH, June CH.
Extensive replicative capacity of human central memory T cells.
J Immunol 172(11): 6675-83, 2004. [Text Abstract on PubMed]
16 Nemoto S, Fergusson MM, Finkel T.
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.
Science 306(5704): 2105-8, 2004. [Text Abstract on PubMed]
17 Nemoto S, Finkel T.
Ageing and the mystery at Arles.
Nature 429(6988): 149-52, 2004. [Text Abstract on PubMed]
18 Ohtsubo T, Rovira II, Starost MF, Liu C, Finkel T.
Xanthine oxidoreductase is an endogenous regulator of cyclooxygenase-2.
Circ Res 95(11): 1118-24, 2004. [Text Abstract on PubMed]
19 Wang J, Marschner S, Finkel TH.
CXCR4 engagement is required for HIV-1-induced L-selectin shedding.
Blood 103(4): 1218-21, 2004. [Text Abstract on PubMed]
20 Yin J, Chen MF, Finkel TH.
Differential gene expression during HIV-1 infection analyzed by suppression subtractive hybridization.
AIDS 18(4): 587-96, 2004. [Text Abstract on PubMed]
21 Feuerstein N, Shivers D, Chen F, Eisenberg RA, Finkel TH.
Chronic GVH prevents anergy in bone marrow self-reactive B cells: a selective increase in post-endoplasmic reticulum processing and trafficking to the cell surface of autoreactive IgM receptors.
Int Immunol 15(8): 975-85, 2003. [Text Abstract on PubMed]
22 Finkel T.
Ageing: a toast to long life.
Nature 425(6954): 132-3, 2003. [Text Abstract on PubMed]
23 Finkel T.
Neutrophils with a license to kill: permeabilized, not stirred.
Dev Cell 4(2): 146-8, 2003. [Text Abstract on PubMed]
24 Finkel T.
Oxidant signals and oxidative stress.
Curr Opin Cell Biol 15(2): 247-54, 2003. [Text Abstract on PubMed]
25 Hill JM, Zalos G, Halcox JP, Schenke WH, Waclawiw MA, Quyyumi AA, Finkel T.
Circulating endothelial progenitor cells, vascular function, and cardiovascular risk.
N Engl J Med 348(7): 593-600, 2003. [Text Abstract on PubMed]
26 Mills EM, Banks ML, Sprague JE, Finkel T.
Pharmacology: uncoupling the agony from ecstasy.
Nature 426(6965): 403-4, 2003. [Text Abstract on PubMed]
27 Selliah N, Shackelford J, Wang JF, Traynor F, Yin J, Finkel TH.
T cell signaling and apoptosis in HIV disease.
Immunol Res 27(2-3): 247-60, 2003. [Text Abstract on PubMed]
28 Ichida M, Nemoto S, Finkel T.
Identification of a specific molecular repressor of the peroxisome proliferator-activated receptor gamma Coactivator-1 alpha (PGC-1alpha).
J Biol Chem 277(52): 50991-5, 2002. [Text Abstract on PubMed]
29 Kovacs B, Maus MV, Riley JL, Derimanov GS, Koretzky GA, June CH, Finkel TH.
Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation.
Proc Natl Acad Sci U S A 99(23): 15006-11, 2002. [Text Abstract on PubMed]
30 Marschner S, Hünig T, Cambier JC, Finkel TH.
Ligation of human CD4 interferes with antigen-induced activation of primary T cells.
Immunol Lett 82(1-2): 131-9, 2002. [Text Abstract on PubMed]
31 Mills EM, Xu D, Fergusson MM, Combs CA, Xu Y, Finkel T.
Regulation of cellular oncosis by uncoupling protein 2.
J Biol Chem 277(30): 27385-92, 2002. [Text Abstract on PubMed]
32 Nemoto S, Finkel T.
Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway.
Science 295(5564): 2450-2, 2002. [Text Abstract on PubMed]
33 Nguyen DT, Rovira II, Finkel T.
Regulation of the Werner helicase through a direct interaction with a subunit of protein kinase A.
FEBS Lett 521(1-3): 170-4, 2002. [Text Abstract on PubMed]
34 Savitsky PA, Finkel T.
Redox regulation of Cdc25C.
J Biol Chem 277(23): 20535-40, 2002. [Text Abstract on PubMed]
35 Sullivan DM, Levine RL, Finkel T.
Detection and affinity purification of oxidant-sensitive proteins using biotinylated glutathione ethyl ester.
Methods Enzymol 353: 101-13, 2002. [Text Abstract on PubMed]
36 Xu D, Finkel T.
A role for mitochondria as potential regulators of cellular life span.
Biochem Biophys Res Commun 294(2): 245-8, 2002. [Text Abstract on PubMed]
37 Xu D, Rovira II, Finkel T.
Oxidants painting the cysteine chapel: redox regulation of PTPs.
Dev Cell 2(3): 251-2, 2002. [Text Abstract on PubMed]
38 Finkel T.
Reactive oxygen species and signal transduction.
IUBMB Life 52(1-2): 3-6, 2001. [Text Abstract on PubMed]
39 Ichida M, Finkel T.
Ras regulates NFAT3 activity in cardiac myocytes.
J Biol Chem 276(5): 3524-30, 2001. [Text Abstract on PubMed]
40 Myers LK, Higgins GC, Finkel TH, Reed AM, Thompson JW, Walton RC, Hendrickson J, Kerr NC, Pandya-Lipman RK, Shlopov BV, Stastny P, Postlethwaite AE, Kang AH.
Juvenile arthritis and autoimmunity to type II collagen.
Arthritis Rheum 44(8): 1775-81, 2001. [Text Abstract on PubMed]
41 Selliah N, Finkel TH.
Biochemical mechanisms of HIV induced T cell apoptosis.
Cell Death Differ 8(2): 127-36, 2001. [Text Abstract on PubMed]
42 Selliah N, Finkel TH.
HIV-1 NL4-3, but not IIIB, inhibits JAK3/STAT5 activation in CD4(+) T cells.
Virology 286(2): 412-21, 2001. [Text Abstract on PubMed]
43 Cron RQ, Finkel TH.
Nabumetone induced pseudoporphyria in childhood.
J Rheumatol 27(7): 1817-8, 2000. [Text Abstract on PubMed]
44 Eisenberg R, Schumacher HR, Finkel TH, Ehrlich GE.
Joseph Lee Hollander, MD, 1910--2000.
Arthritis Rheum 43(7): 1430, 2000. [Text Abstract on PubMed]
45 Finkel T, Holbrook NJ.
Oxidants, oxidative stress and the biology of ageing.
Nature 408(6809): 239-47, 2000. [Text Abstract on PubMed]
46 Finkel T.
Redox-dependent signal transduction.
FEBS Lett 476(1-2): 52-4, 2000. [Text Abstract on PubMed]
47 Hsich E, Segal BH, Pagano PJ, Rey FE, Paigen B, Deleonardis J, Hoyt RF, Holland SM, Finkel T.
Vascular effects following homozygous disruption of p47(phox) : An essential component of NADPH oxidase.
Circulation 101(11): 1234-6, 2000. [Text Abstract on PubMed]
48 Marbán E, Bolli R, Breitwieser G, Busse R, Dietz H, Endoh M, Finkel T, Kass D, Lowenstein C, Rabinovitch M, Tomaselli G.
Under new management: A six-month progress report on Circulation Research.
Circ Res 86(2): 111-3, 2000. [Text Abstract on PubMed]
49 Nemoto S, Takeda K, Yu ZX, Ferrans VJ, Finkel T.
Role for mitochondrial oxidants as regulators of cellular metabolism.
Mol Cell Biol 20(19): 7311-8, 2000. [Text Abstract on PubMed]
50 Sullivan DM, Finkel T.
Expression of Rho GTPases using adenovirus vectors.
Methods Enzymol 325: 303-14, 2000. [Text Abstract on PubMed]
51 Sullivan DM, Wehr NB, Fergusson MM, Levine RL, Finkel T.
Identification of oxidant-sensitive proteins: TNF-alpha induces protein glutathiolation.
Biochemistry 39(36): 11121-8, 2000. [Text Abstract on PubMed]
52 Xu D, Neville R, Finkel T.
Homocysteine accelerates endothelial cell senescence.
FEBS Lett 470(1): 20-4, 2000. [Text Abstract on PubMed]
53 Angkachatchai V, Finkel TH.
ADP-ribosylation of rho by C3 ribosyltransferase inhibits IL-2 production and sustained calcium influx in activated T cells.
J Immunol 163(7): 3819-25, 1999. [Text Abstract on PubMed]
54 Casella CR, Rapaport EL, Finkel TH.
Vpu increases susceptibility of human immunodeficiency virus type 1-infected cells to fas killing.
J Virol 73(1): 92-100, 1999. [Text Abstract on PubMed]
55 Doanes AM, Hegland DD, Sethi R, Kovesdi I, Bruder JT, Finkel T.
VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases.
Biochem Biophys Res Commun 255(2): 545-8, 1999. [Text Abstract on PubMed]
56 Finkel T.
Signal transduction by reactive oxygen species in non-phagocytic cells.
J Leukoc Biol 65(3): 337-40, 1999. [Text Abstract on PubMed]
57 Finkel T.
Thinking globally, acting locally. The promise of cardiovascular gene therapy.
Circ Res 84(12): 1471-2, 1999. [Text Abstract on PubMed]
58 Finkel TH, Hunter DJ, Paisley JE, Finkel RS, Larsen GL.
Drug-induced lupus in a child after treatment with zafirlukast (Accolate).
J Allergy Clin Immunol 103(3 Pt 1): 533-4, 1999. [Text Abstract on PubMed]
59 Finkel TH.
Potential use of a caspase against HIV.
JAMA 282(11): 1021-2, 1999. [Text Abstract on PubMed]
60 Hegland DD, Sullivan DM, Rovira II, Li A, Kovesdi I, Bruder JT, Finkel T.
Regulation of endothelial cell adherens junctions by a Ras-dependent signal transduction pathway.
Biochem Biophys Res Commun 260(2): 371-6, 1999. [Text Abstract on PubMed]
61 Ito H, Rovira II, Bloom ML, Takeda K, Ferrans VJ, Quyyumi AA, Finkel T.
Endothelial progenitor cells as putative targets for angiostatin.
Cancer Res 59(23): 5875-7, 1999. [Text Abstract on PubMed]
62 Lee AC, Fenster BE, Ito H, Takeda K, Bae NS, Hirai T, Yu ZX, Ferrans VJ, Howard BH, Finkel T.
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species.
J Biol Chem 274(12): 7936-40, 1999. [Text Abstract on PubMed]
63 Li A, Prasad A, Mincemoyer R, Satorius C, Epstein N, Finkel T, Quyyumi AA.
Relationship of the C242T p22phox gene polymorphism to angiographic coronary artery disease and endothelial function.
Am J Med Genet 86(1): 57-61, 1999. [Text Abstract on PubMed]
64 Li AE, Ito H, Rovira II, Kim KS, Takeda K, Yu ZY, Ferrans VJ, Finkel T.
A role for reactive oxygen species in endothelial cell anoikis.
Circ Res 85(4): 304-10, 1999. [Text Abstract on PubMed]
65 Marschner S, Freiberg BA, Kupfer A, Hünig T, Finkel TH.
Ligation of the CD4 receptor induces activation-independent down-regulation of L-selectin.
Proc Natl Acad Sci U S A 96(17): 9763-8, 1999. [Text Abstract on PubMed]
66 Moldovan L, Irani K, Moldovan NI, Finkel T, Goldschmidt-Clermont PJ.
The actin cytoskeleton reorganization induced by Rac1 requires the production of superoxide.
Antioxid Redox Signal 1(1): 29-43, 1999. [Text Abstract on PubMed]
67 Paterson RK, Bluethmann H, Tseng P, Dunlap A, Finkel TH.
Development and function of autospecific dual TCR+ T lymphocytes.
Int Immunol 11(1): 113-9, 1999. [Text Abstract on PubMed]
68 Tanaka K, Zou JP, Takeda K, Ferrans VJ, Sandford GR, Johnson TM, Finkel T, Epstein SE.
Effects of human cytomegalovirus immediate-early proteins on p53-mediated apoptosis in coronary artery smooth muscle cells.
Circulation 99(13): 1656-9, 1999. [Text Abstract on PubMed]
69 Zhou YF, Shou M, Guetta E, Guzman R, Unger EF, Yu ZX, Zhang J, Finkel T, Epstein SE.
Cytomegalovirus infection of rats increases the neointimal response to vascular injury without consistent evidence of direct infection of the vascular wall.
Circulation 100(14): 1569-75, 1999. [Text Abstract on PubMed]
70 Bousvaros A, Sundel R, Thorne GM, McIntosh K, Cohen M, Erdman DD, Perez-Atayde A, Finkel TH, Colin AA.
Parvovirus B19-associated interstitial lung disease, hepatitis, and myositis.
Pediatr Pulmonol 26(5): 365-9, 1998. [Text Abstract on PubMed]
71 Doanes AM, Irani K, Goldschmidt-Clermont PJ, Finkel T.
A requirement for rac1 in the PDGF-stimulated migration of fibroblasts and vascular smooth cells.
Biochem Mol Biol Int 45(2): 279-87, 1998. [Text Abstract on PubMed]
72 Finkel T.
Oxygen radicals and signaling.
Curr Opin Cell Biol 10(2): 248-53, 1998. [Text Abstract on PubMed]
73 Kim KS, Takeda K, Sethi R, Pracyk JB, Tanaka K, Zhou YF, Yu ZX, Ferrans VJ, Bruder JT, Kovesdi I, Irani K, Goldschmidt-Clermont P, Finkel T.
Protection from reoxygenation injury by inhibition of rac1.
J Clin Invest 101(9): 1821-6, 1998. [Text Abstract on PubMed]
74 Lee L, Irani K, Finkel T.
Bcl-2 regulates nonapoptotic signal transduction: inhibition of c-Jun N-terminal kinase (JNK) activation by IL-1 beta and hydrogen peroxide.
Mol Genet Metab 64(1): 19-24, 1998. [Text Abstract on PubMed]
75 Pracyk JB, Tanaka K, Hegland DD, Kim KS, Sethi R, Rovira II, Blazina DR, Lee L, Bruder JT, Kovesdi I, Goldshmidt-Clermont PJ, Irani K, Finkel T.
A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy.
J Clin Invest 102(5): 929-37, 1998. [Text Abstract on PubMed]
76 Rapaport E, Casella CR, Ikl , Mustafa F, Isaak D, Finkel TH.
Mapping of HIV-1 determinants of apoptosis in infected T cells.
Virology 252(2): 407-17, 1998. [Text Abstract on PubMed]
77 Rozdzial MM, Pleiman CM, Cambier JC, Finkel TH.
pp56Lck mediates TCR zeta-chain binding to the microfilament cytoskeleton.
J Immunol 161(10): 5491-9, 1998. [Text Abstract on PubMed]
78 Selliah N, Finkel TH.
Cutting edge: JAK3 activation and rescue of T cells from HIV gp120-induced unresponsiveness.
J Immunol 160(12): 5697-701, 1998. [Text Abstract on PubMed]
79 Tanaka K, Pracyk JB, Takeda K, Yu ZX, Ferrans VJ, Deshpande SS, Ozaki M, Hwang PM, Lowenstein CJ, Irani K, Finkel T.
Expression of Id1 results in apoptosis of cardiac myocytes through a redox-dependent mechanism.
J Biol Chem 273(40): 25922-8, 1998. [Text Abstract on PubMed]
80 Casella CR, Finkel TH.
Mechanisms of lymphocyte killing by HIV.
Curr Opin Hematol 4(1): 24-31, 1997. [Text Abstract on PubMed]
81 Cotton MF, Ikle DN, Rapaport EL, Marschner S, Tseng PO, Kurrle R, Finkel TH.
Apoptosis of CD4+ and CD8+ T cells isolated immediately ex vivo correlates with disease severity in human immunodeficiency virus type 1 infection.
Pediatr Res 42(5): 656-64, 1997. [Text Abstract on PubMed]
82 Erdman DD, Anderson BC, Török TJ, Finkel TH, Anderson LJ.
Possible transmission of parvovirus B19 from intravenous immune globulin.
J Med Virol 53(3): 233-6, 1997. [Text Abstract on PubMed]
83 Harrell RL, Rajanayagam S, Doanes AM, Guzman RJ, Hirschowitz EA, Crystal RG, Epstein SE, Finkel T.
Inhibition of vascular smooth muscle cell proliferation and neointimal accumulation by adenovirus-mediated gene transfer of cytosine deaminase.
Circulation 96(2): 621-7, 1997. [Text Abstract on PubMed]
84 Irani K, Xia Y, Zweier JL, Sollott SJ, Der CJ, Fearon ER, Sundaresan M, Finkel T, Goldschmidt-Clermont PJ.
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts.
Science 275(5306): 1649-52, 1997. [Text Abstract on PubMed]
85 Leung DY, Sullivan KE, Brown-Whitehorn TF, Fehringer AP, Allen S, Finkel TH, Washington RL, Makida R, Schlievert PM.
Association of toxic shock syndrome toxin-secreting and exfoliative toxin-secreting Staphylococcus aureus with Kawasaki syndrome complicated by coronary artery disease.
Pediatr Res 42(3): 268-72, 1997. [Text Abstract on PubMed]
86 Moldovan NI, Milliken EE, Irani K, Chen J, Sohn RH, Finkel T, Goldschmidt-Clermont PJ.
Regulation of endothelial cell adhesion by profilin.
Curr Biol 7(1): 24-30, 1997. [Text Abstract on PubMed]
87 Moore KA, Sethi R, Doanes AM, Johnson TM, Pracyk JB, Kirby M, Irani K, Goldschmidt-Clermont PJ, Finkel T.
Rac1 is required for cell proliferation and G2/M progression.
Biochem J 326 ( Pt 1): 17-20, 1997. [Text Abstract on PubMed]
88 Cotton MF, Cassella C, Rapaport EL, Tseng PO, Marschner S, Finkel TH.
Apoptosis in HIV-1 Infection.
Behring Inst Mitt(97): 220-31, 1996. [Text Abstract on PubMed]
89 Crawford LE, Milliken EE, Irani K, Zweier JL, Becker LC, Johnson TM, Eissa NT, Crystal RG, Finkel T, Goldschmidt-Clermont PJ.
Superoxide-mediated actin response in post-hypoxic endothelial cells.
J Biol Chem 271(43): 26863-7, 1996. [Text Abstract on PubMed]
90 Epstein SE, Speir E, Zhou YF, Guetta E, Leon M, Finkel T.
The role of infection in restenosis and atherosclerosis: focus on cytomegalovirus.
Lancet 348 Suppl 1: s13-7, 1996. [Text Abstract on PubMed]
91 Johnson TM, Epstein SE, Finkel T.
Apoptosis in vascular disease: opportunities for genetic therapeutic intervention.
Semin Interv Cardiol 1(3): 195-202, 1996. [Text Abstract on PubMed]
92 Johnson TM, Yu ZX, Ferrans VJ, Lowenstein RA, Finkel T.
Reactive oxygen species are downstream mediators of p53-dependent apoptosis.
Proc Natl Acad Sci U S A 93(21): 11848-52, 1996. [Text Abstract on PubMed]
93 Paterson RL, Lack G, Domenico JM, Delespesse G, Leung DY, Finkel TH, Gelfand EW.
Triggering through CD40 promotes interleukin-4-induced CD23 production and enhanced soluble CD23 release in atopic disease.
Eur J Immunol 26(9): 1979-84, 1996. [Text Abstract on PubMed]
94 Sulciner DJ, Irani K, Yu ZX, Ferrans VJ, Goldschmidt-Clermont P, Finkel T.
rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation.
Mol Cell Biol 16(12): 7115-21, 1996. [Text Abstract on PubMed]
95 Sundaresan M, Yu ZX, Ferrans VJ, Sulciner DJ, Gutkind JS, Irani K, Goldschmidt-Clermont PJ, Finkel T.
Regulation of reactive-oxygen-species generation in fibroblasts by Rac1.
Biochem J 318 ( Pt 2): 379-82, 1996. [Text Abstract on PubMed]
96 Zhou YF, Guetta E, Yu ZX, Finkel T, Epstein SE.
Human cytomegalovirus increases modified low density lipoprotein uptake and scavenger receptor mRNA expression in vascular smooth muscle cells.
J Clin Invest 98(9): 2129-38, 1996. [Text Abstract on PubMed]
97 Zhou YF, Leon MB, Waclawiw MA, Popma JJ, Yu ZX, Finkel T, Epstein SE.
Association between prior cytomegalovirus infection and the risk of restenosis after coronary atherectomy.
N Engl J Med 335(9): 624-30, 1996. [Text Abstract on PubMed]
98 Finkel T, Epstein SE.
Gene therapy for vascular disease.
FASEB J 9(10): 843-51, 1995. [Text Abstract on PubMed]
99 Finkel TH, Tudor-Williams G, Banda NK, Cotton MF, Curiel T, Monks C, Baba TW, Ruprecht RM, Kupfer A.
Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes.
Nat Med 1(2): 129-34, 1995. [Text Abstract on PubMed]
100 Rozdzial MM, Malissen B, Finkel TH.
Tyrosine-phosphorylated T cell receptor zeta chain associates with the actin cytoskeleton upon activation of mature T lymphocytes.
Immunity 3(5): 623-33, 1995. [Text Abstract on PubMed]
101 Speir E, Huang ES, Modali R, Leon MB, Shawl F, Finkel T, Epstein SE.
Interaction of human cytomegalovirus with p53: possible role in coronary restenosis.
Scand J Infect Dis Suppl 99: 78-81, 1995. [Text Abstract on PubMed]
102 Sundaresan M, Yu ZX, Ferrans VJ, Irani K, Finkel T.
Requirement for generation of H2O2 for platelet-derived growth factor signal transduction.
Science 270(5234): 296-9, 1995. [Text Abstract on PubMed]
103 Epstein SE, Speir E, Unger EF, Guzman RJ, Finkel T.
The basis of molecular strategies for treating coronary restenosis after angioplasty.
J Am Coll Cardiol 23(6): 1278-88, 1994. [Text Abstract on PubMed]
104 Finkel T, Theriot JA, Dise KR, Tomaselli GF, Goldschmidt-Clermont PJ.
Dynamic actin structures stabilized by profilin.
Proc Natl Acad Sci U S A 91(4): 1510-4, 1994. [Text Abstract on PubMed]
105 Finkel TH, Banda NK.
Indirect mechanisms of HIV pathogenesis: how does HIV kill T cells?
Curr Opin Immunol 6(4): 605-15, 1994. [Text Abstract on PubMed]
106 Finkel TH, Török TJ, Ferguson PJ, Durigon EL, Zaki SR, Leung DY, Harbeck RJ, Gelfand EW, Saulsbury FT, Hollister JR.
Chronic parvovirus B19 infection and systemic necrotising vasculitis: opportunistic infection or aetiological agent?
Lancet 343(8908): 1255-8, 1994. [Text Abstract on PubMed]
107 Guzman RJ, Hirschowitz EA, Brody SL, Crystal RG, Epstein SE, Finkel T.
In vivo suppression of injury-induced vascular smooth muscle cell accumulation using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene.
Proc Natl Acad Sci U S A 91(22): 10732-6, 1994. [Text Abstract on PubMed]
108 Irani K, Herzlinger S, Finkel T.
Ras proteins regulate multiple mitogenic pathways in A10 vascular smooth muscle cells.
Biochem Biophys Res Commun 202(3): 1252-8, 1994. [Text Abstract on PubMed]
109 Paterson RK, Burkly LC, Kurahara DK, Dunlap A, Flavell RA, Finkel TH.
Thymic development in human CD4 transgenic mice. Positive selection occurs after commitment to the CD8 lineage.
J Immunol 153(8): 3491-503, 1994. [Text Abstract on PubMed]
110 Rozdzial MM, Kubo RT, Turner SL, Finkel TH.
Developmental regulation of the TCR zeta-chain. Differential expression and tyrosine phosphorylation of the TCR zeta-chain in resting immature and mature T lymphocytes.
J Immunol 153(4): 1563-80, 1994. [Text Abstract on PubMed]
111 Speir E, Modali R, Huang ES, Leon MB, Shawl F, Finkel T, Epstein SE.
Potential role of human cytomegalovirus and p53 interaction in coronary restenosis.
Science 265(5170): 391-4, 1994. [Text Abstract on PubMed]
112 Epstein SE, Speir E, Finkel T.
Do antisense approaches to the problem of restenosis make sense?
Circulation 88(3): 1351-3, 1993. [Text Abstract on PubMed]
113 Finkel T, Duc J, Fearon ER, Dang CV, Tomaselli GF.
Detection and modulation in vivo of helix-loop-helix protein-protein interactions.
J Biol Chem 268(1): 5-8, 1993. [Text Abstract on PubMed]
114 Guzman RJ, Lemarchand P, Crystal RG, Epstein SE, Finkel T.
Efficient and selective adenovirus-mediated gene transfer into vascular neointima.
Circulation 88(6): 2838-48, 1993. [Text Abstract on PubMed]
115 Guzman RJ, Lemarchand P, Crystal RG, Epstein SE, Finkel T.
Efficient gene transfer into myocardium by direct injection of adenovirus vectors.
Circ Res 73(6): 1202-7, 1993. [Text Abstract on PubMed]
116 Banda NK, Bernier J, Kurahara DK, Kurrle R, Haigwood N, Sekaly RP, Finkel TH.
Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis.
J Exp Med 176(4): 1099-106, 1992. [Text Abstract on PubMed]
117 Fearon ER, Finkel T, Gillison ML, Kennedy SP, Casella JF, Tomaselli GF, Morrow JS, Van Dang C.
Karyoplasmic interaction selection strategy: a general strategy to detect protein-protein interactions in mammalian cells.
Proc Natl Acad Sci U S A 89(17): 7958-62, 1992. [Text Abstract on PubMed]
118 Finkel TH, Kappler JW, Marrack PC.
Immature thymocytes are protected from deletion early in ontogeny.
Proc Natl Acad Sci U S A 89(8): 3372-4, 1992. [Text Abstract on PubMed]
119 Blackman MA, Finkel TH, Kappler J, Cambier J, Marrack P.
Altered antigen receptor signaling in anergic T cells from self-tolerant T-cell receptor beta-chain transgenic mice.
Proc Natl Acad Sci U S A 88(15): 6682-6, 1991. [Text Abstract on PubMed]
120 Finkel TH, Kubo RT, Cambier JC.
T-cell development and transmembrane signaling: changing biological responses through an unchanging receptor.
Immunol Today 12(2): 79-85, 1991. [Text Abstract on PubMed]
121 Punt JA, Kubo RT, Saito T, Finkel TH, Kathiresan S, Blank KJ, Hashimoto Y.
Surface expression of a T cell receptor beta (TCR-beta) chain in the absence of TCR-alpha, -delta, and -gamma proteins.
J Exp Med 174(4): 775-83, 1991. [Text Abstract on PubMed]
122 Finkel TH, Cambier JC, Kubo RT, Born WK, Marrack P, Kappler JW.
The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR.
Cell 58(6): 1047-54, 1989. [Text Abstract on PubMed]
123 Finkel TH, Marrack P, Kappler JW, Kubo RT, Cambier JC.
Alpha beta T cell receptor and CD3 transduce different signals in immature T cells. Implications for selection and tolerance.
J Immunol 142(9): 3006-12, 1989. [Text Abstract on PubMed]
124 Marrack P, Blackman M, Burgert HG, McCormack JM, Cambier J, Finkel TH, Kappler J.
T-cell repertoire and thymus.
Cold Spring Harb Symp Quant Biol 54 Pt 1: 105-10, 1989. [Text Abstract on PubMed]
125 Finkel TH, Pabst MJ, Suzuki H, Guthrie LA, Forehand JR, Phillips WA, Johnston RB.
Priming of neutrophils and macrophages for enhanced release of superoxide anion by the calcium ionophore ionomycin. Implications for regulation of the respiratory burst.
J Biol Chem 262(26): 12589-96, 1987. [Text Abstract on PubMed]
126 Carney WP, Petit D, Hamer P, Der CJ, Finkel T, Cooper GM, Lefebvre M, Mobtaker H, Delellis R, Tischler AS.
Monoclonal antibody specific for an activated RAS protein.
Proc Natl Acad Sci U S A 83(19): 7485-9, 1986. [Text Abstract on PubMed]
127 Der CJ, Finkel T, Cooper GM.
Biological and biochemical properties of human rasH genes mutated at codon 61.
Cell 44(1): 167-76, 1986. [Text Abstract on PubMed]
128 Finkel T, Cooper GM.
Detection of a molecular complex between ras proteins and transferrin receptor.
Cell 36(4): 1115-21, 1984. [Text Abstract on PubMed]
129 Finkel T, Der CJ, Cooper GM.
Activation of ras genes in human tumors does not affect localization, modification, or nucleotide binding properties of p21.
Cell 37(1): 151-8, 1984. [Text Abstract on PubMed]
130 Colavitti R, Finkel T.
Reactive oxygen species as mediators of cellular senescence.
IUBMB Life 57(4-5): 277-81, [Text Abstract on PubMed]
131 Finkel TH, McDuffie M, Kappler JW, Marrack P, Cambier JC.
Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking.
Nature 330(6144): 179-81, [Text Abstract on PubMed]