John A Hammer's Web Page

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Publications

1 Remmert K, Olszewski TE, Bowers MB, Dimitrova M, Ginsburg A, Hammer JA.
CARMIL is a bona fide capping protein interactant.
J Biol Chem 279(4): 3068-77, 2004. [Text Abstract on PubMed]
2 Snyder GE, Sakamoto T, Hammer JA, Sellers JR, Selvin PR.
Nanometer localization of single green fluorescent proteins: evidence that myosin V walks hand-over-hand via telemark configuration.
Biophys J 87(3): 1776-83, 2004. [Text Abstract on PubMed]
3 Wang F, Thirumurugan K, Stafford WF, Hammer JA, Knight PJ, Sellers JR.
Regulated conformation of myosin V.
J Biol Chem 279(4): 2333-6, 2004. [Text Abstract on PubMed]
4 Rudolf R, Kögel T, Kuznetsov SA, Salm T, Schlicker O, Hellwig A, Hammer JA, Gerdes HH.
Myosin Va facilitates the distribution of secretory granules in the F-actin rich cortex of PC12 cells.
J Cell Sci 116(Pt 7): 1339-48, 2003. [Text Abstract on PubMed]
5 Wagner W, Hammer JA.
Myosin V and the endoplasmic reticulum: the connection grows.
J Cell Biol 163(6): 1193-6, 2003. [Text Abstract on PubMed]
6 Hammer JA, Wu XS.
Rabs grab motors: defining the connections between Rab GTPases and motor proteins.
Curr Opin Cell Biol 14(1): 69-75, 2002. [Text Abstract on PubMed]
7 Loftus SK, Larson DM, Baxter LL, Antonellis A, Chen Y, Wu X, Jiang Y, Bittner M, Hammer JA, Pavan WJ.
Mutation of melanosome protein RAB38 in chocolate mice.
Proc Natl Acad Sci U S A 99(7): 4471-6, 2002. [Text Abstract on PubMed]
8 Virador VM, Muller J, Wu X, Abdel-Malek ZA, Yu ZX, Ferrans VJ, Kobayashi N, Wakamatsu K, Ito S, Hammer JA, Hearing VJ.
Influence of alpha-melanocyte-stimulating hormone and ultraviolet radiation on the transfer of melanosomes to keratinocytes.
FASEB J 16(1): 105-7, 2002. [Text Abstract on PubMed]
9 Wu X, Wang F, Rao K, Sellers JR, Hammer JA.
Rab27a is an essential component of melanosome receptor for myosin Va.
Mol Biol Cell 13(5): 1735-49, 2002. [Text Abstract on PubMed]
10 Wu XS, Rao K, Zhang H, Wang F, Sellers JR, Matesic LE, Copeland NG, Jenkins NA, Hammer JA.
Identification of an organelle receptor for myosin-Va.
Nat Cell Biol 4(4): 271-8, 2002. [Text Abstract on PubMed]
11 Al-Haddad A, Shonn MA, Redlich B, Blocker A, Burkhardt JK, Yu H, Hammer JA, Weiss DG, Steffen W, Griffiths G, Kuznetsov SA.
Myosin Va bound to phagosomes binds to F-actin and delays microtubule-dependent motility.
Mol Biol Cell 12(9): 2742-55, 2001. [Text Abstract on PubMed]
12 Haddad EK, Wu X, Hammer JA, Henkart PA.
Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice.
J Cell Biol 152(4): 835-42, 2001. [Text Abstract on PubMed]
13 Jung G, Remmert K, Wu X, Volosky JM, Hammer JA.
The Dictyostelium CARMIL protein links capping protein and the Arp2/3 complex to type I myosins through their SH3 domains.
J Cell Biol 153(7): 1479-97, 2001. [Text Abstract on PubMed]
14 Petralia RS, Wang YX, Sans N, Worley PF, Hammer JA, Wenthold RJ.
Glutamate receptor targeting in the postsynaptic spine involves mechanisms that are independent of myosin Va.
Eur J Neurosci 13(9): 1722-32, 2001. [Text Abstract on PubMed]
15 Wu X, Rao K, Bowers MB, Copeland NG, Jenkins NA, Hammer JA.
Rab27a enables myosin Va-dependent melanosome capture by recruiting the myosin to the organelle.
J Cell Sci 114(Pt 6): 1091-100, 2001. [Text Abstract on PubMed]
16 Walker ML, Burgess SA, Sellers JR, Wang F, Hammer JA, Trinick J, Knight PJ.
Two-headed binding of a processive myosin to F-actin.
Nature 405(6788): 804-7, 2000. [Text Abstract on PubMed]
17 Wang F, Chen L, Arcucci O, Harvey EV, Bowers B, Xu Y, Hammer JA, Sellers JR.
Effect of ADP and ionic strength on the kinetic and motile properties of recombinant mouse myosin V.
J Biol Chem 275(6): 4329-35, 2000. [Text Abstract on PubMed]
18 Wu X, Hammer JA.
Making sense of melanosome dynamics in mouse melanocytes.
Pigment Cell Res 13(4): 241-7, 2000. [Text Abstract on PubMed]
19 Wu X, Jung G, Hammer JA.
Functions of unconventional myosins.
Curr Opin Cell Biol 12(1): 42-51, 2000. [Text Abstract on PubMed]
20 Redowicz MJ, Hammer JA, Bowers B, Zolkiewski M, Ginsburg A, Korn ED, Rau DC.
Flexibility of Acanthamoeba myosin rod minifilaments.
Biochemistry 38(22): 7243-52, 1999. [Text Abstract on PubMed]
21 Carragher BO, Cheng N, Wang ZY, Korn ED, Reilein A, Belnap DM, Hammer JA, Steven AC.
Structural invariance of constitutively active and inactive mutants of acanthamoeba myosin IC bound to F-actin in the rigor and ADP-bound states.
Proc Natl Acad Sci U S A 95(26): 15206-11, 1998. [Text Abstract on PubMed]
22 Wang ZY, Wang F, Sellers JR, Korn ED, Hammer JA.
Analysis of the regulatory phosphorylation site in Acanthamoeba myosin IC by using site-directed mutagenesis.
Proc Natl Acad Sci U S A 95(26): 15200-5, 1998. [Text Abstract on PubMed]
23 Wu X, Bowers B, Rao K, Wei Q, Hammer JA .
Visualization of melanosome dynamics within wild-type and dilute melanocytes suggests a paradigm for myosin V function In vivo.
J Cell Biol 143(7): 1899-918, 1998. [Text Abstract on PubMed]
24 Wu X, Kocher B, Wei Q, Hammer JA.
Myosin Va associates with microtubule-rich domains in both interphase and dividing cells.
Cell Motil Cytoskeleton 40(3): 286-303, 1998. [Text Abstract on PubMed]
25 Wang ZY, Sakai J, Matsudaira PT, Baines IC, Sellers JR, Hammer JA, Korn ED.
The amino acid sequence of the light chain of Acanthamoeba myosin IC.
J Muscle Res Cell Motil 18(3): 395-8, 1997. [Text Abstract on PubMed]
26 Wei Q, Wu X, Hammer JA.
The predominant defect in dilute melanocytes is in melanosome distribution and not cell shape, supporting a role for myosin V in melanosome transport.
J Muscle Res Cell Motil 18(5): 517-27, 1997. [Text Abstract on PubMed]
27 Wu X, Bowers B, Wei Q, Kocher B, Hammer JA.
Myosin V associates with melanosomes in mouse melanocytes: evidence that myosin V is an organelle motor.
J Cell Sci 110 ( Pt 7): 847-59, 1997. [Text Abstract on PubMed]
28 Zolkiewski M, Redowicz MJ, Korn ED, Hammer JA, Ginsburg A.
Two-state thermal unfolding of a long dimeric coiled-coil: the Acanthamoeba myosin II rod.
Biochemistry 36(25): 7876-83, 1997. [Text Abstract on PubMed]
29 Hammer JA, Jung G.
The sequence of the dictyostelium myo J heavy chain gene predicts a novel, dimeric, unconventional myosin with a heavy chain molecular mass of 258 kDa.
J Biol Chem 271(12): 7120-7, 1996. [Text Abstract on PubMed]
30 Jung G, Wu X, Hammer JA.
Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions.
J Cell Biol 133(2): 305-23, 1996. [Text Abstract on PubMed]
31 Morita YS, Jung G, Hammer JA, Fukui Y.
Localization of Dictyostelium myoB and myoD to filopodia and cell-cell contact sites using isoform-specific antibodies.
Eur J Cell Biol 71(4): 371-9, 1996. [Text Abstract on PubMed]
32 Terasaki M, Jaffe LA, Hunnicutt GR, Hammer JA.
Structural change of the endoplasmic reticulum during fertilization: evidence for loss of membrane continuity using the green fluorescent protein.
Dev Biol 179(2): 320-8, 1996. [Text Abstract on PubMed]
33 Hammer JA.
Regulation of Dictyostelium myosin II by phosphorylation: what is essential and what is important?
J Cell Biol 127(6 Pt 2): 1779-82, 1994. [Text Abstract on PubMed]
34 Hammer JA.
The structure and function of unconventional myosins: a review.
J Muscle Res Cell Motil 15(1): 1-10, 1994. [Text Abstract on PubMed]
35 Jung G, Hammer JA.
The actin binding site in the tail domain of Dictyostelium myosin IC (myoC) resides within the glycine- and proline-rich sequence (tail homology region 2).
FEBS Lett 342(2): 197-202, 1994. [Text Abstract on PubMed]
36 Jung G, Fukui Y, Martin B, Hammer JA.
Sequence, expression pattern, intracellular localization, and targeted disruption of the Dictyostelium myosin ID heavy chain isoform.
J Biol Chem 268(20): 14981-90, 1993. [Text Abstract on PubMed]
37 Urrutia RA, Jung G, Hammer JA.
The Dictyostelium myosin IE heavy chain gene encodes a truncated isoform that lacks sequences corresponding to the actin binding site in the tail.
Biochim Biophys Acta 1173(2): 225-9, 1993. [Text Abstract on PubMed]
38 Hammer JA, Jung G.
Molecular cloning of protozoan myosin I heavy chain genes.
J Cell Sci Suppl 14: 37-40, 1991. [Text Abstract on PubMed]
39 Hammer JA.
Novel myosins.
Trends Cell Biol 1(2-3): 50-6, 1991. [Text Abstract on PubMed]
40 Wessels D, Murray J, Jung G, Hammer JA, Soll DR.
Myosin IB null mutants of Dictyostelium exhibit abnormalities in motility.
Cell Motil Cytoskeleton 20(4): 301-15, 1991. [Text Abstract on PubMed]
41 Halsall DJ, Hammer JA.
A second isoform of chicken brush border myosin I contains a 29-residue inserted sequence that binds calmodulin.
FEBS Lett 267(1): 126-30, 1990. [Text Abstract on PubMed]
42 Horowitz JA, Hammer JA.
A new Acanthamoeba myosin heavy chain. Cloning of the gene and immunological identification of the polypeptide.
J Biol Chem 265(33): 20646-52, 1990. [Text Abstract on PubMed]
43 Jung G, Hammer JA.
Generation and characterization of Dictyostelium cells deficient in a myosin I heavy chain isoform.
J Cell Biol 110(6): 1955-64, 1990. [Text Abstract on PubMed]
44 Korn ED, Hammer JA.
Myosin I.
Curr Opin Cell Biol 2(1): 57-61, 1990. [Text Abstract on PubMed]
45 Jung G, Saxe CL, Kimmel AR, Hammer JA.
Dictyostelium discoideum contains a gene encoding a myosin I heavy chain.
Proc Natl Acad Sci U S A 86(16): 6186-90, 1989. [Text Abstract on PubMed]
46 Jung G, Schmidt CJ, Hammer JA.
Myosin I heavy-chain genes of Acanthamoeba castellanii: cloning of a second gene and evidence for the existence of a third isoform.
Gene 82(2): 269-80, 1989. [Text Abstract on PubMed]
47 Korn ED, Atkinson MA, Brzeska H, Hammer JA, Jung G, Lynch TJ.
Structure-function studies on Acanthamoeba myosins IA, IB, and II.
J Cell Biochem 36(1): 37-50, 1988. [Text Abstract on PubMed]
48 Korn ED, Hammer JA.
Myosins of nonmuscle cells.
Annu Rev Biophys Biophys Chem 17: 23-45, 1988. [Text Abstract on PubMed]
49 Jung G, Korn ED, Hammer JA.
The heavy chain of Acanthamoeba myosin IB is a fusion of myosin-like and non-myosin-like sequences.
Proc Natl Acad Sci U S A 84(19): 6720-4, 1987. [Text Abstract on PubMed]
50 Hammer JA, Jung G, Korn ED.
Genetic evidence that Acanthamoeba myosin I is a true myosin.
Proc Natl Acad Sci U S A 83(13): 4655-9, 1986. [Text Abstract on PubMed]
51 Hammer JA, Korn ED, Paterson BM.
Isolation of a non-muscle myosin heavy chain gene from Acanthamoeba.
J Biol Chem 261(4): 1949-56, 1986. [Text Abstract on PubMed]
52 Albanesi JP, Fujisaki H, Hammer JA, Korn ED, Jones R, Sheetz MP.
Monomeric Acanthamoeba myosins I support movement in vitro.
J Biol Chem 260(15): 8649-52, 1985. [Text Abstract on PubMed]
53 Côté GP, Albanesi JP, Ueno T, Hammer JA, Korn ED.
Purification from Dictyostelium discoideum of a low-molecular-weight myosin that resembles myosin I from Acanthamoeba castellanii.
J Biol Chem 260(8): 4543-6, 1985. [Text Abstract on PubMed]
54 Hammer JA, Korn ED, Paterson BM.
Acanthamoeba myosin IA, IB, and II heavy chains are synthesized in vitro from Acanthamoeba messenger RNA.
J Biol Chem 259(18): 11157-9, 1984. [Text Abstract on PubMed]
55 Hammer JA, Sellers JR, Korn ED.
Phosphorylation and activation of smooth muscle myosin by Acanthamoeba myosin I heavy chain kinase.
J Biol Chem 259(5): 3224-9, 1984. [Text Abstract on PubMed]
56 Albanesi JP, Hammer JA, Korn ED.
The interaction of F-actin with phosphorylated and unphosphorylated myosins IA and IB from Acanthamoeba castellanii.
J Biol Chem 258(16): 10176-81, 1983. [Text Abstract on PubMed]
57 Hammer JA, Albanesi JP, Korn ED.
Purification and characterization of a myosin I heavy chain kinase from Acanthamoeba castellanii.
J Biol Chem 258(16): 10168-75, 1983. [Text Abstract on PubMed]
58 Hammer JA, Rannels DE.
Effects of halothane on protein synthesis and degradation in rabbit pulmonary macrophages.
Am Rev Respir Dis 124(1): 50-5, 1981. [Text Abstract on PubMed]
59 Hammer JA, Rannels DE.
Protein turnover in pulmonary macrophages. Utilization of amino acids derived from protein degradation.
Biochem J 198(1): 53-65, 1981. [Text Abstract on PubMed]