Laboratory of Kidney and
Electrolyte Metabolism (LKEM)
Mark A Knepper, MD, PhD, Principal Investigator
This laboratory studies kidney function in health and disease. The major objectives are to understand renal transport and osmotic regulation at molecular and cellular levels and determine how these processes are integrated to account for normal and abnormal renal function. The processes investigated include water and ion transport, gene expression, apoptosis, intracellular signaling and membrane trafficking. The laboratory provides training opportunities at all levels from high school to postdoctoral. (See also: Research Training and Career Development Programs at the National Heart, Lung, and Blood Institute.)
The sections and principal investigators of LKEM are:
The Urine Proteomic Website (UroProt) compiles
and disseminates protocols that support the identification
and measurement of urinary biomarkers of disease processes.
For more information, please visit the Urine
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