Scientific Supercomputing at the NIH

Mendel

Description

Mendel is a comprehensive package for exact statistical genetic analysis of qualitative and quantitative traits.

Mendel is intended to be used interactively on Helix. Note that Mendel expects all the appropriate input files to be available in the current directory, or else program errors will be observed.

Version

Type mendel on command line

Sample session

Sample files can be copied from /usr/local/mendel/Example_Input/.
% cd /data/user/mendel_run % ls Control00.in Locus0.in Map0.in Ped0.in Variable0.in % mendel -c Control00.in MENDEL RUN COMPLETED. % more Mendel0.out WELCOME TO MENDEL, VERSION 8.0.1 (c) COPYRIGHT KENNETH LANGE, 1985-2008 ALL COMMERCIAL RIGHTS RESERVED TIME OF DAY : 13:13 MONTH/DAY/YEAR: 07/25/2006 FOR PUBLICATION PURPOSES, PLEASE CITE THE REFERENCE: LANGE K, CANTOR R, HORVATH S, PEROLA M, SABATTI C, SINSHEIMER J, SOBEL E (2001) MENDEL VERSION 4.0: A COMPLETE PACKAGE FOR THE EXACT GENETIC ANALYSIS OF DISCRETE TRAITS IN PEDIGREE AND POPULATION DATA SETS. AMER J HUM GENETICS 69(SUPPLEMENT):A1886 CONTENT OF CONTROL FILE Myrun.in: OUTPUT_FILE = Mendel0.out LOCUS_FILE = Locus0.in MAP_FILE = Map0.in PEDIGREE_FILE = Ped0.in VARIABLE_FILE = Variable0.in ANALYSIS_OPTION = Mistyping MODEL = 1 CONTENT OF LOCUS FILE Locus0.in: LOCUS = Egomania CHROMOSOME = Autosome 2 ALLELES 2 PHENOTYPES [....]
Tip: The programs are installed in /usr/local/mendel. If you use the program frequently, it may be convenient to add this directory to your path. For a single session: setenv PATH /usr/local/mendel:$PATH (csh or tcsh) PATH=/usr/local/mendel:$PATH; export PATH (bash) To add this directory to your path at login time, add the appropriate line above to your ~/.cshrc or ~/.bashrc file.

Documentation

http://www.genetics.ucla.edu/software/Mendel_documentation.pdf