Type 1 Diabetes Special Statutory Funding Program
Clinical Studies Recruiting Type 1 Diabetes Patients and Family Members
CLINICAL TRIALS
Clinical Islet Transplantation Consortium (CIT) : The goal of the CIT05 studies is to determine the proportion of subjects who are insulin independent at 75 ± 5 days following one islet cell infusion among subjects treated with an experimental islet transplant immunosuppression regimen which includes rituximab and excludes tacrolimus.
Study Names:Strategies to Improve Long Term Islet Graft Survival, B-Lymphocyte Immunotherapy in Islet Transplantation, Efficacy of Islet after Kidney Transplantation , Peritransplant Deoxyspergualin in Islet Transplantation in Type 1 Diabetes, Islet Transplantation in Type 1 Diabetes with LEA29Y Maintenance Therapy, Islet Transplantation in Type 1 Diabetes
The Environmental Determinants of Diabetes in the Young (TEDDY) : This study is identifying infants at high-risk for developing type 1 diabetes and following them through adolescence in the search for environmental factors that may trigger disease onset.
Study Name:The Environmental Determinants of Diabetes in the Young
Trial to Reduce IDDM in the Genetically at Risk (TRIGR) : This randomized, double blinded intervention study is comparing the development of type 1 diabetes in infants who are weaned onto a hydrolysate of cow’s milk formula, in which many of the cow proteins have been broken down, versus standard cow’s milk formula.
Study Name:Trial to Reduce IDDM in those at Genetic Risk
Type 1 Diabetes TrialNet (TrialNet) : This network supports clinical trials of agents to slow the progression of type 1 diabetes in new-onset patients and to prevent the disease in at-risk patients.
Study Names:TrialNet-MMF/DZB, TrialNet Natural History Study, The Rituximab Study, Nutritional Intervention to Prevent Diabetes , Oral Insulin Study , TEST, test, CTLA-4 Ig (Abatacept) in Recent Onset Diabetes
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