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NCI Highlights
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Phase of Trial
Title
Type of Trial
Status of Trial
Age Range
Sponsor of Trial
Protocol IDs
Version:
Health Professional
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Last Modified:
1/29/2009
 
First Published:
2/20/2004
1.
Phase III Randomized Study of Oxaliplatin (OXAL) Plus 5-Fluorouracil (5-FU)/Leucovorin (CF) With or Without Cetuximab (C225) After Curative Resection for Patients with Stage III Colon Cancer (Note: All Treatment Arms Containing Irinotecan Closed to Accrual as of 6/1/2005)
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Treatment
Active
18 to 69
NCI
NCCTG-N0147
ECOG-N0147, N0147, NCT00079274
Last Modified:
1/29/2009
 
First Published:
9/16/2005
2.
Phase III Randomized Study of Oxaliplatin, Leucovorin Calcium, and Fluorouracil With Versus Without Bevacizumab in Patients With Resected Stage II Colon Cancer and at High Risk for Recurrence Based on Molecular Markers
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Treatment
Active
18 and over
NCI
ECOG-E5202
E5202, NCT00217737
Last Modified:
1/29/2009
 
First Published:
12/9/2005
3.
Phase III Randomized Study of Cetuximab and/or Bevacizumab in Combination With Either Oxaliplatin, Fluorouracil, and Leucovorin Calcium (FOLFOX) OR Irinotecan Hydrochloride, Fluorouracil, and Leucovorin Calcium (FOLFIRI) in Patients With Previously Untreated Metastatic Adenocarcinoma of the Colon or Rectum
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase III
Treatment
Active
18 and over
NCI
CALGB-C80405
C80405, SWOG-C80405, NCT00265850
Last Modified:
12/13/2008
 
First Published:
2/17/2006
4.
Phase I/II Study of Dose-Dense and Dose-Intense Capecitabine in Combination With Alternating Full-Dose Irinotecan Hydrochloride and Oxaliplatin With or Without Bevacizumab in Patients With Metastatic or Locally Advanced Unresectable Colorectal Cancer or Other Solid Tumors
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase II, Phase I
Treatment
Active
18 and over
NCI
CASE-1205
NCI-7325, 7325, NCT00296062
Last Modified:
1/22/2009
 
First Published:
10/24/2006
5.
Phase I/II Study of Erlotinib Hydrochloride and Cetuximab in Patients With Advanced Gastrointestinal, Head and Neck, Non-Small Cell Lung, or Colorectal Cancer
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase II, Phase I
Treatment
Active
18 and over
NCI
VU-VICC-GI-0622
VICC-GI-0622, 6980, NCI-6980, NCT00397384
Last Modified:
1/9/2009
 
First Published:
9/16/2008
6.
Phase I/II Randomized Study of Erlotinib Hydrochloride in Inhibiting Epidermal Growth Factor Receptor Signaling in Aberrant Crypt Foci in Patients With Curatively Treated Stage I-III Colorectal Cancer or Adenoma
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase II, Phase I
Biomarker/Laboratory analysis, Treatment
Active
18 and over
NCI
UCIRVINE-UCI06-8-01
UCI06-8-01, NCT00754494
First Published:
12/15/2008
7.
Phase I/II Study of Nonmyeloablative Lymphodepleting Conditioning Comprising Cyclophosphamide and Fludarabine Phosphate Followed by Anti-CEA TCR-Gene Engineered Autologous Lymphocytes and High-Dose Aldesleukin in Patients With Metastatic Cancer That Expresses CEA
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase II, Phase I
Biomarker/Laboratory analysis, Treatment
Active
18 and over
NCI
NCI-09-C-0047
09-C-0047, NCI-P08404, NCT00809978
Last Modified:
10/6/2008
 
First Published:
10/25/2004
8.
Phase II Study of Intrahepatic Arterial Infusion of Melphalan With Venous Filtration Via Peripheral Hepatic Perfusion in Patients With Unresectable Primary or Metastatic Liver Cancer
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase II
Treatment
Active
16 and over
NCI
NCI-04-C-0273
NCI-6332, DELCATH-G990039, NCT00096083
Last Modified:
1/24/2009
 
First Published:
11/22/2004
9.
Phase II Study of Treatment Selection Based Upon Tumor Thymidylate Synthase Expression in Previously Untreated Patients With Metastatic Colorectal Cancer
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase II
Treatment
Active
18 and over
NCI
ECOG-E4203
E4203, NCT00098787
Last Modified:
11/16/2008
 
First Published:
1/24/2005
10.
Phase II Randomized Study of Adjuvant Vaccine Therapy Comprising Vaccinia-CEA-MUC-1-TRICOM Vaccine (PANVAC-V) and Fowlpox-CEA-MUC-1-TRICOM Vaccine (PANVAC-F) Administered With Autologous Dendritic Cells or Sargramostim (GM-CSF) in Patients With Completely Resected Hepatic or Pulmonary Metastases Secondary to Colorectal Cancer
Phase
Type
Status
Age
Sponsor
Protocol IDs
Phase II
Treatment
Active
18 and over
NCI
DUMC-5883-04-6RO
NCT00103142
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