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Agent Name Propane
CAS Number 74-98-6
Formula C3-H8
Major Category Other Chemicals
Synonyms A-108; Dimethylmethane; HC 290; Hydrocarbon Propellant A-108; LPG; Liquefied petroleum gas; Petroleum gas, liquefied; Propane; Propyl hydride; Propyldihydride; R 290; n-Propane; [ChemIDplus] UN1978
Category Simple Asphyxiants
Description Colorless, odorless gas. [Note: A foul-smelling odorant is often added when used for fuel purposes. Shipped as a liquefied compressed gas.]; [NIOSH]
Sources/Uses Used as a fuel, solvent, refrigerant, and propellant; [Hawley]
Comments Propane is a simple asphyxiant. [LaDou, p. 518] Possible frostbite from contact with liquid; [NIOSH] "Critical Effects" for aliphatic hydrocarbon gases are CNS depression; cardiac sensitization; [ACGIH] Propane is in the list of "Some volatile substances which may be abused by inhalation" published on the web site of the U.N. International Drug Control Programme, indicating its potential to cause narcosis in workers. [Reference #1] Evaporating liquid can cause frostbite; Inhalation of high concentrations can cause CNS depression and cardiac arrhythmias; [ICSC]
Reference Link Volatile Substance Abuse
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 1000 ppm
PEL (OSHA) 1000 ppm
MAK 1000 ppm
IDLH (NIOSH) 2100 ppm
Excerpts from Documentation for IDLHs It has been reported that brief inhalation exposures to 10,000 ppm propane cause no symptoms in humans [Braker and Mossman 1980]. Propane is considered to be a simple asphyxiant [ACGIH 1991].
Odor Threshold Low 12225 ppm
Odor Threshold High 20005 ppm
Lethal Concentration LC50 (rats) > 800,000 ppm/15m
Explanatory Notes IDLH = 10% LEL; Odor threshold from AIHA; For TLV, see Aliphatic hydrocarbon gases: Alkane (C1-C4); [ACGIH]; Flash point = -156 deg F;
Flammability (NFPA) 4: burns readily
Adverse Effects
Neurotoxin CNS Solvent Syndrome
Other Poison Simple Asphyxiant
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: PROPANE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:





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Last updated: September, 2008