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Use these instructions in addition to those in the PHS 398. |
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You will submit your application using the PHS 398. Assemble and paginate it as one document. The instructions below are in addition to -- not a substitute for -- those in the PHS 398.
Face Page
Complete all items as instructed.
Submit one face page only (projects and cores use cover pages, not additional face pages).
This is the first page of the application; number remaining pages consecutively.
Form Page 2
Use this form for an abstract -- a succinct but accurate description of the overall multiproject application, addressing the major, common theme of the program. Stay within the space provided. List all performance sites that will conduct research.
Under "key personnel," list the PI (or PIs if the initiative includes the option of multiple PIs) of the multiproject application followed by the project leaders of the research projects and cores, other key personnel, and other significant contributors.
Form Page 3
Do not use this page. In its place, prepare a detailed table of contents that will let reviewers locate information pertinent to the overall application as well as to each project and core.
- Identify each project by number (e.g., project 1), title, and project leader.
- Identify each core by letter (e.g., core A), title, and core leader.
- Include the page number for the composite budget and budgets of each project and core.
Keep in mind that each project and core will get its own Form Page 3 and its own review.
Form Page 4
Do not use this page. Instead, use the table format below to create a budget for the entire application for all proposed years of support.
As stated before, include the page number for the budget in the table of contents. Do not justify budget elements here; put a justification in the budget of each project and core.
Sample Consolidated Direct Cost Budget for All Years of Support
| Component |
Year 1 |
Year 2 |
Year 3 |
Year 4 |
Year 5 |
All Years |
| Project 1. Vector development |
125,000 |
130,000 |
135,200 |
140,608 |
146,232 |
677,040 |
| Project 2. Immunology studies in mice |
125,000 |
130,000 |
135,200 |
140,608 |
146,232 |
677,040 |
| Project 3. Attenuated vectors as vaccines in macaques |
100,000 |
104,000 |
108,160 |
112,486 |
116,985 |
541,631 |
| Core A. Administrative Core |
50,000 |
52,000 |
54,080 |
56,243 |
58,493 |
270,816 |
| Core B. Vaccine Production Core |
25,000 |
50,000 |
52,000 |
54,080 |
56,243 |
237,323 |
| Totals |
425,000 |
466,000 |
484,640 |
504,025 |
524,185 |
2,403,850 |
Form Page 5
Complete the total direct cost entries for all requested budget periods (years) and total direct cost for the entire period of support.
Biographical Sketch Format Page
Put biographical sketches of professional personnel for all components at the end of the application with the PI's first followed by the project leaders of the research projects and cores, other key personnel, and other significant contributors.
Resources Format Page
Do not use this page. Give essential information in the individual research project and core sections.
Research Plan -- Program Overview
This narrative section summarizes the overall Research Plan; items 2 to 5 are limited to 25 pages.
A multiproject application is a confederation of interrelated research projects, each capable of standing on its own scientific merit but complementing one another. This important section lets a group of investigators show the program's conceptual unity by describing the scientific problems to be addressed and laying out a broad research strategy to address them.
As the strategy develops, describe how each project and core fits into the overall scheme. Summarize special features in the environment and resources that make this application strong, unique, or both.
Appendix
Appendix information must be directly relevant to the application. If data are crucial to the Research Plan, put the data in your application, not an Appendix.
You may have only one Appendix for the whole application. Clearly cross-reference any materials that relate to a project or core.
In addition to NIH's general rules, a multiproject application can have up to three publications or patent-related items for each core or project -- for details see If You Need an
Appendix in the NIH Grant Cycle: Application to Renewal. Always read the NIH Guide announcement to see if there are additional directions.
Submit your Appendix on a CD in PDF format, or prepare five paper sets.
Checklist Form Page
Complete one for the entire application, and place it at the end of the application.
Other Support Format Page
Do not use this page. We will request this information just-in-time, before issuing a grant award.
Introduction for a Resubmission
If you need to resubmit, include an introduction of up to three pages to address reviewers' comments for the overall application as well as for each project and core, as needed.
Note: you must request permission from your program officer to resubmit your application.
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