Unique Features of Neurotrophin Receptor Signaling |
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| Launch in standalone player | |
| Air date: | Monday, March 29, 2004, 12:00:00 PM |
| Category: | Neuroscience |
| Runtime: | 90 minutes |
| NLM Title: | Unique features of neurotrophin receptor signaling [electronic resource] / Moses V. Chao. |
| Series: | Neuroscience lecture series |
| Author: | Chao, Moses V. National Institutes of Health (U.S.) |
| Publisher: | [Bethesda, Md. : National Institutes of Health, 2004] |
| Other Title(s): | Neuroscience lecture series |
| Abstract: | (CIT): The generation and differentiation of neurons and glial cells are dependent upon cell-cell interactions mediated by a wide variety of growth factors and cytokines. Dr. Chao's laboratory is interested in receptor-mediated mechanisms that direct cell differentiation versus cell proliferation in the nervous system. A major goal is to identify the biochemical steps that provide specificity in NGF signaling. Control of cell survival and death by neurotrophins is dictated by an unusual transduction system consisting of two transmembrane receptors, the TrkA tyrosine kinase and the p75 neurotrophin receptor, a member of the TNF receptor superfamily. The structural and biochemical features of these two receptors are being defined together with their intracellular signaling mechanisms. For more information, visit Moses Chao NIH Neuroscience Seminar Series. |
| Subjects: | Nerve Growth Factors Receptor Protein-Tyrosine Kinases Receptors, Nerve Growth Factor Signal Transduction |
| Publication Types: | Government Publications Lectures |
| Rights: | This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely. |
| Download: | Download
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| NLM Classification: | WL 104 |
| NLM ID: | 101268414 |
| CIT File ID: | 11944 |
| CIT Live ID: | 3164 |
| Permanent link: | http://videocast.nih.gov/launch.asp?11944 |