| | This journal provides immediate access to some articles. Perspective News from Arabidopsis on the Meiotic Roles of Blap75/Rmi1 and Top3α Charles I. White PMCID: PMC2588658 Interview Taken to School: An Interview with the Honorable Judge John E. Jones, III Jane Gitschier PMCID: PMC2588113 Research Articles Practical Issues in Imputation-Based Association Mapping Yongtao Guan and Matthew Stephens PMCID: PMC2585794 Topoisomerase 3α and RMI1 Suppress Somatic Crossovers and Are Essential for Resolution of Meiotic Recombination Intermediates in Arabidopsis thaliana Frank Hartung, Stefanie Suer, Alexander Knoll, Rebecca Wurz-Wildersinn, and Holger Puchta PMCID: PMC2588661 Asymmetry of Chromosome Replichores Renders the DNA Translocase Activity of FtsK Essential for Cell Division and Cell Shape Maintenance in Escherichia coli Christian Lesterlin, Carine Pages, Nelly Dubarry, Santanu Dasgupta, and François Cornet PMCID: PMC2585057 Loss of Kindlin-1 Causes Skin Atrophy and Lethal Neonatal Intestinal Epithelial Dysfunction Siegfried Ussar, Markus Moser, Moritz Widmaier, Emanuel Rognoni, Christian Harrer, Orsolya Genzel-Boroviczeny, and Reinhard Fässler PMCID: PMC2585060 Spt2p Defines a New Transcription-Dependent Gross Chromosomal Rearrangement Pathway Nilabja Sikdar, Soma Banerjee, Han Zhang, Stephanie Smith, and Kyungjae Myung PMCID: PMC2585797 Targeting the X Chromosome during Spermatogenesis Induces Y Chromosome Transmission Ratio Distortion and Early Dominant Embryo Lethality in Anopheles gambiae Nikolai Windbichler, Philippos Aris Papathanos, and Andrea Crisanti PMCID: PMC2585807 Evolutionary Diversification of Plant Shikimate Kinase Gene Duplicates Geoffrey Fucile, Shannon Falconer, and Dinesh Christendat PMCID: PMC2593004 The Genomic Analysis of Lactic Acidosis and Acidosis Response in Human Cancers Julia Ling-Yu Chen, Joseph E. Lucas, Thies Schroeder, Seiichi Mori, Jianli Wu, Joseph Nevins, Mark Dewhirst, Mike West, and Jen-Tsan Chi PMCID: PMC2585811 Effects of cis and trans Genetic Ancestry on Gene Expression in African Americans Alkes L. Price, Nick Patterson, Dustin C. Hancks, Simon Myers, David Reich, Vivian G. Cheung, and Richard S. Spielman PMCID: PMC2586034 Apoptosis Maintains Oocyte Quality in Aging Caenorhabditis elegans Females Sara Andux and Ronald E. Ellis PMCID: PMC2585808 Disruption of AP1S1, Causing a Novel Neurocutaneous Syndrome, Perturbs Development of the Skin and Spinal Cord Alexandre Montpetit, Stéphanie Côté, Edna Brustein, Christian A. Drouin, Line Lapointe, Michèle Boudreau, Caroline Meloche, Régen Drouin, Thomas J. Hudson, Pierre Drapeau, and Patrick Cossette PMCID: PMC2585812 Genome-Wide siRNA-Based Functional Genomics of Pigmentation Identifies Novel Genes and Pathways That Impact Melanogenesis in Human Cells Anand K. Ganesan, Hsiang Ho, Brian Bodemann, Sean Petersen, Jayavani Aruri, Shiney Koshy, Zachary Richardson, Lu Q. Le, Tatiana Krasieva, Michael G. Roth, Pat Farmer, and Michael A. White PMCID: PMC2585813 Novel Low Abundance and Transient RNAs in Yeast Revealed by Tiling Microarrays and Ultra High–Throughput Sequencing Are Not Conserved Across Closely Related Yeast Species Albert Lee, Kasper Daniel Hansen, James Bullard, Sandrine Dudoit, and Gavin Sherlock PMCID: PMC2601015 The Stringent Response and Cell Cycle Arrest in Escherichia coli Daniel J. Ferullo and Susan T. Lovett PMCID: PMC2586660 Compensatory Interactions between Sir3p and the Nucleosomal LRS Surface Imply Their Direct Interaction Anne Norris, Mario A. Bianchet, and Jef D. Boeke PMCID: PMC2587916 The Chromosomal High-Affinity Binding Sites for the Drosophila Dosage Compensation Complex Tobias Straub, Charlotte Grimaud, Gregor D. Gilfillan, Angelika Mitterweger, and Peter B. Becker PMCID: PMC2586088 The Repertoire and Dynamics of Evolutionary Adaptations to Controlled Nutrient-Limited Environments in Yeast David Gresham, Michael M. Desai, Cheryl M. Tucker, Harry T. Jenq, Dave A. Pai, Alexandra Ward, Christopher G. DeSevo, David Botstein, and Maitreya J. Dunham PMCID: PMC2586090 The Population Genetics of dN/dS Sergey Kryazhimskiy and Joshua B. Plotkin PMCID: PMC2596312 Duplication and Gene Conversion in the Drosophila melanogaster Genome Naoki Osada and Hideki Innan PMCID: PMC2588116 A Simple Screen to Identify Promoters Conferring High Levels of Phenotypic Noise Nikki E. Freed, Olin K. Silander, Bärbel Stecher, Alex Böhm, Wolf-Dietrich Hardt, and Martin Ackermann PMCID: PMC2588653 Shaping Skeletal Growth by Modular Regulatory Elements in the Bmp5 Gene Catherine Guenther, Luiz Pantalena-Filho, and David M. Kingsley PMCID: PMC2592695 The Arabidopsis BLAP75/Rmi1 Homologue Plays Crucial Roles in Meiotic Double-Strand Break Repair Liudmila Chelysheva, Daniel Vezon, Katia Belcram, Ghislaine Gendrot, and Mathilde Grelon PMCID: PMC2588655 Genetic and Computational Identification of a Conserved Bacterial Metabolic Module Cara C. Boutte, Balaji S. Srinivasan, Jason A. Flannick, Antal F. Novak, Andrew T. Martens, Serafim Batzoglou, Patrick H. Viollier, and Sean Crosson PMCID: PMC2597717 Developmental Constraints on Vertebrate Genome Evolution Julien Roux and Marc Robinson-Rechavi PMCID: PMC2600815 Novel Association of HK1 with Glycated Hemoglobin in a Non-Diabetic Population: A Genome-Wide Evaluation of 14,618 Participants in the Women's Genome Health Study Guillaume Paré, Daniel I. Chasman, Alexander N. Parker, David M. Nathan, Joseph P. Miletich, Robert Y. Zee, and Paul M. Ridker PMCID: PMC2596965 Sexually Antagonistic “Zygotic Drive” of the Sex Chromosomes William R. Rice, Sergey Gavrilets, and Urban Friberg PMCID: PMC2596966 Physcomitrella patens DCL3 Is Required for 22–24 nt siRNA Accumulation, Suppression of Retrotransposon-Derived Transcripts, and Normal Development Sung Hyun Cho, Charles Addo-Quaye, Ceyda Coruh, M. Asif Arif, Zhaorong Ma, Wolfgang Frank, and Michael J. Axtell PMCID: PMC2600652 The Golgin GMAP210/TRIP11 Anchors IFT20 to the Golgi Complex John A. Follit, Jovenal T. San Agustin, Fenghui Xu, Julie A. Jonassen, Rajeev Samtani, Cecilia W. Lo, and Gregory J. Pazour PMCID: PMC2602600 Gata3 Acts Downstream of β-Catenin Signaling to Prevent Ectopic Metanephric Kidney Induction David Grote, Sami Kamel Boualia, Abdallah Souabni, Calli Merkel, Xuan Chi, Frank Costantini, Thomas Carroll, and Maxime Bouchard PMCID: PMC2597718 Ion Channel Clustering at the Axon Initial Segment and Node of Ranvier Evolved Sequentially in Early Chordates Alexis S. Hill, Atsuo Nishino, Koichi Nakajo, Giuxin Zhang, Jaime R. Fineman, Michael E. Selzer, Yasushi Okamura, and Edward C. Cooper PMCID: PMC2597720 Corrections Correction: Exploring Microbial Diversity and Taxonomy Using SSU rRNA Hypervariable Tag Sequencing Susan M. Huse, Les Dethlefsen, Julie A. Huber, David Mark Welch, David A. Relman, and Mitchell L. Sogin PMCID: PMC2597897 Corrects: Susan M. Huse, et al. Exploring Microbial Diversity and Taxonomy Using SSU rRNA Hypervariable Tag Sequencing. PLoS Genet. 2008 November; 4(11): e1000255. Correction: Hypermutable Non-Synonymous Sites Are under Stronger Negative Selection Steffen Schmidt, Anna Gerasimova, Fyodor A. Kondrashov, Ivan A. Adzhubei, Alexey S. Kondrashov, and Shamil Sunyaev PMCID: PMC2605301 Corrects: Steffen Schmidt, et al. Hypermutable Non-Synonymous Sites Are under Stronger Negative Selection. PLoS Genet. 2008 November; 4(11): e1000281. |
