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Abstract

Grant Number:	3U01AT002550-01S1
Project Title:	Mindfulness Meditation: Regulating Eating and Obesi(RMI)

PI Information:	Name	Email	Title
	KRISTELLER, JEAN L.	pykris@isugw.indstate.edu	PROFESSOR

Abstract: DESCRIPTION (provided by applicant): Obesity is epidemic within America, with marked increases in related medical problems such as diabetes and heart disease. Obesity often reflects chronic loss of control around eating, and involves disregulation of physiological, emotional and behavioral systems. While cognitive-behavioral therapies (CBT) have demonstrated promise, long term maintenance of weight change, particularly in individuals with binge eating patterns, is uncommon; most individuals gradually return to former patterns of overeating and weight levels. Interventions utilizing mindfulness meditation are showing promise in treating related problems, including depression, addictions and anxiety. Furthermore, meditation-based interventions may engage different mediating mechanisms than do CBT interventions. Our recent work shows that eating focused meditation techniques assist obese individuals with binge eating problems to normalize their eating behaviors, mood, metabolic regulation, and increase reported internalization of control, independent of weight change. This study expands our MB-EAT (Mindfulness-Based Eating Awareness Therapy) program to explicitly address long-term weight loss, and compares it to a widely used meditation program (MBSR) and to a standard CBT intervention, to further explore mechanisms of change. Obese men and women reporting binge eating from three communities (approximate N=225) will be randomized to 3 conditions: 1) the 12-session MB-EAT intervention, 2) a general MBSR program, or 3) a standardized CBT comparison condition. Primary outcome variables will be changes in eating behavior and weight, and associated measures of depression, self-esteem, and diet; secondary variables include metabolic variables sensitive to dietary and weight change (i.e., glucose and insulin regulation), and mediator variables including level of engagement with the treatment components, including level of practice, changes in mindfulness, and experiences of increased control and awareness. Participants will be evaluated pre- and post-treatment, and at 1, 3, 6, 12 and 18 months follow up. This data could provide support for the integration of mindfulness meditation into comprehensive treatment programs for obesity and binge eating, and would determine if there is additional benefit from a focused-meditation approach.

Public Health Relevance:
This Public Health Relevance is not available.

Thesaurus Terms:
alternative medicine, binge eating disorder, cognitive behavior therapy, human therapy evaluation, meditation, obesity, weight control, weight loss
awareness, clinical trial, depression, eating, glucose, health behavior, insulin sensitivity /resistance, quality of life, self concept, triglyceride
behavioral /social science research tag, clinical research, human subject, patient oriented research, questionnaire

Institution:	INDIANA STATE UNIVERSITY
	TERRE HAUTE, IN 47809
Fiscal Year:	2005
Department:	PSYCHOLOGY
Project Start:	29-SEP-2004
Project End:	30-JUN-2008
ICD:	NATIONAL CENTER FOR COMPLEMENTARY & ALTERNATIVE MEDICINE
IRG:	ZRG1

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