The NCI CCR announces a course for NIH Fellows: Redox Biology
Examination & Course Evaluation Now Available!
Overview
Recent advances in the biochemistry of redox active species and radicals are beginning to be translated into improvements in prevention and treatment of cancer. Traditionally, these reactive species like superoxide, hydrogen peroxide and nitric oxide are associated with toxicity, however, nitric oxide is useful in the treatment of angina and cardiovascular disease. Also, nitric oxide is involved in cancer tumor angiogenesis and apoptosis of cancer cells. The course will overview how redox active species and radicals are generated, their effects on the cellular and physiological level, how they alter carcinogenesis, angiogenesis and proliferation in animal models of cancer, and how nitric oxide alters patient imaging profiles and response to cancer therapy.
The Redox Biology course will be held on Tuesday afternoons from 4-6 p.m. on September 30 to November 25, 2008 at the Bethesda Campus, Bldg. 50, Rooms 1227/1233. Redox Biology is designed to provide an overview of general principles of nitric oxide biochemistry, cell biology, signal transduction, physiology, carcinogenesis, chemoprevention, angiogenesis, therapy, immunology and epidemiology. The participation of NIH Postdoctoral and Clinical Fellows interested in redox biology is encouraged.
Links and Related Training Opportunities
This course is part of a developing curriculum for training NCI clinical and postdoctoral fellows. Translational Research in Clinical Oncology (TRACO), which runs from Sept.-Dec. concerns new methods for diagnosing and treating cancer. TRACO complements other topics in human diseases and therapies covered in "Demystifying Medicine for PhDs" which runs from January to May. For additional training opportunities at NIH view http://www.training.nih.gov.
Location and Time
Redox Biology will consist of 2 one hour lectures held on Tuesdays, 4-6 p.m., Bldg. 50, Rms. 1227/1233. Each session will have 2 50-min lectures with ample time for discussion and analysis. A handout for each lecture will be distributed on site.
Registration
Deadline for Registration is September 25, 2008. For more information contact Dr. Terry Moody, by e-mail (moodyt@mail.nih.gov) by FAX (301-480-4323) or by phone (301-451-9451). There is no registration fee.
Certificate
There is no fee for this course. Participants, who register for the course, may receive a certificate of completion after completion of the final examination.
| Faculty | ||
Steering Commitee: |
Faculty: |
|
David Wink, PhD |
S. Ambs PhD |
R. Pluta MD |
Terry Moody, PhD |
P. Hussain PhD |
D. Roberts PhD |
Jonathan Wiest, PhD |
M. Krishna PhD |
H. Young, PhD |
J. Mitchell PhD |
D. Wink PhD |
|
| T. Moody PhD | G. Yeh PhD |
|
Schedule and Speakers |
||
Date |
Lecture |
Speakers: 4 p.m., 5 p.m. |
Sept. 30 |
Introduction, Redox Chemistry |
T. Moody, D. Wink |
Oct. 7 |
REDOX WORKSHOP |
|
Oct.14 |
Redox Biology, Signal Transduction |
D. Wink, T. Moody |
Oct. 21 |
Angiogenesis, CNS |
D. Roberts, R. Pluta |
Oct. 28 |
Epidemiology, Inflammation |
S. Ambs, P. Hussain |
Nov. 4 |
Carcinogenesis, Immunology |
G. Yeh, H. Young |
Nov. 11 |
NO CLASS |
|
Nov. 18 |
NADPH oxidases, Imaging |
T. Leto, M. Krishna |
Nov. 25 |
Redox Enzymes, Cancer Therapy |
L. Ridnour, J. Mitchell |
PowerPoint Presentations |
||
Date added |
Title |
Size |
| 10/15/2008 | RB Introduction | ~7MB |
| 10/23/2008 | Transduction | ~6MB |
