A post-doctoral position is available to study the cerebrovascular coupling in small animal models. We use a multi-modal approach, which combines functional magnetic resonance imaging, optical imaging and electrophysiology, to answer fundamental questions about cerebral blood flow regulation during spontaneous and stimulation-induced brain activity. Current projects focus on the study of the major neurochemical signaling pathways that translate a change in brain activity into a vascular response and the identification of the smallest vascular unit that adapts independently to brain activity and its spatial and temporal relationship to the cerebral cortical architecture. The lab provides a state-of-the-art 7T/310 mm horizontal animal magnetic resonance imaging scanner, and electrophysiology and optical imaging instrumentation for combined multi-electrode recording and intrinsic signal imaging. All Candidates must have a Ph.D. or equivalent degree in Neurosciences, Physiology, or a related discipline. Candidates with experience in imaging or electrophysiology are particularly encouraged to apply.
Application Instructions:
Applicants should submit a letter of interest outlining experience and research goals, as well as a CV and the names of three references to:
Afonso C. Silva, Ph.D.
Cerebral Microcirculation Unit, NINDS
Building 10, Room B1D106
10 Center Drive, MSC 1065
Bethesda, MD 20892-1065