Neuroscience@NIH - Post-doctoral Openings

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Post-Doctoral Openings

Investigator: Zu-Hang Sheng Affiliation: Synaptic Function Unit, NINDS Position Type: Postdoctoral Fellowship Labs Web Page: http://neuroscience.nih.gov/Lab.asp?Org_ID=56 Description: Postdoctoral positions are available immediately to study the molecular and cellular mechanisms underlying: (1) the transport of synaptic components and mitochondria to mature and developing synapses and (2) the regulation of synaptic vesicle exocytosis. Using a combination of state-of-the-art live cell imaging, biochemistry, cell biology, and electrophysiology, we are characterizing three newly cloned proteins named Snapin, syntaphilin, and syntabulin. With the generation of knockout mice, the physiological roles of Snapin and syntaphilin in the regulation of synaptic veiscle exocytosis and presynaptic function are being revealed (Nature Neuroscience, 1999; Neuron 2000; Nature Cell Biology 2001, J Neuroscience 2005). Using live cell imaging combined with loss-of-function approaches we are conducting a critical assessment of syntabulin’s role in the neuronal trafficking of presynaptic components and mitochondria (Nature Cell Biology 2004; J Cell Biology 2005). Our studies provide a foundation for further studying the biological mechanisms underlying neuronal transport for synaptic assembly and modulation. The lab is equipped with state-of-art imaging (Zeiss LSM510 META confocal). The unique open-lab setup in new Porter Neuroscience Building creates a highly interactive research environment. NIH provides ample training opportunities for postdoctoral fellows. In addition, the Bethesda campus is located in the Washington DC metropolitan area, offering a culturally rich and diverse environment. Candidates for these positions should hold a Ph.D. with research experience in one of these areas: molecular and cellular neurobiology and synaptic electrophysiology, and should have less than five years of postdoctoral experience. Application Instructions: Send CV, statement of research interest, and names of 3 references to: Dr. Zu-Hang Sheng Synaptic Function Unit, NINDS, NIH The Porter Neuroscience Building, Room 3B203 35 Convent Drive, Bethesda, MD 20892-3701 email: shengz@ninds.nih.gov Lab Webpage: http://neuroscience.nih.gov/Lab.asp?Org_ID=56 DHHS and NIH are Equal Opportunity Employers NIH AND DHHS ARE EQUAL OPPORTUNITY EMPLOYERS

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Last updated Tuesday, March 28, 2006