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Carbomer 974
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Brand Name: BufferGel
Drug Class: Microbicides
Carbomer 974, also known as BufferGel, is a type of medicine called a microbicide. Microbicides are substances that protect the body from microorganisms such as bacteria, viruses, and fungi. Microbicides work by either destroying the microbes or preventing them from establishing an infection.

HIV/AIDS-Related Uses
Carbomer 974 is an investigational medicine that is not yet approved by the FDA for use outside of clinical trials. It is being studied for the prevention of sexual transmission of HIV. This medicine does not cure HIV infection or AIDS and is being studied to reduce the risk of passing the virus to other people.

Dosage Form/Administration
Carbomer 974 comes in topical gel form and is applied vaginally with a single-use applicator before intercourse.

Contraindications
Individuals should tell a doctor about any medical problems before taking this medicine.

Possible Side Effects
Along with its desired effects, carbomer 974 may cause some unwanted effects. While not all of these effects are known, vaginal irritation and burning have been reported as the most common side effects.

Drug and Food Interactions
A doctor should be notified of any other medications being taken, including prescription, nonprescription (over-the-counter), or herbal medications.

Clinical Trials
Click here to search ClinicalTrials.gov for trials that use Carbomer 974.

Manufacturer Information
Carbomer 974
  Lubrizol Corporation
  29400 Lakeland Boulevard
  Wickliffe,  OH  44092
    

BufferGel
  ReProtect, Inc.
  703 Stags Head Road
  Baltimore,  MD  21286
  (410) 516-7260
    
Updated April 29, 2007