Disease/Syndrome |
Nasal sinus cancer |
Category |
Cancer, Occupational |
Acute/Chronic |
Chronic |
Synonyms |
Paranasal sinus neoplasms; Sino-nasal cancer; |
Biomedical References |
Search PubMed |
Comments |
Agents associated with sino-nasal cancer include cigarette smoking, wood and leather dust, nickel refining, chromates, mustard gas manufacturing, isopropanol manufacturing (sulfuric acid mists), and possibly formaldehyde and welding. [LaDou, p. 302] Softwood dust is associated with squamous cell carcinoma, and hardwood dust is associated with adenocarcinoma of the nasal cavity. An increased risk exists for sawmill workers, furniture workers, wood products workers, and carpenters. No increased risk exists for workers in forestry, logging, or paper and pulp. [Dement J. Wood Dust. In: Bingham E, Cohrssen B, Powell C, eds. Patty's Toxicology, 5th ed. New York: John Wiley & Sons; 2001:619-49] Seventy percent of patients with sinonasal adenocarcinoma reported in Denmark between 1965 and 1974 had worked for many years in wood-working jobs. [Skov T, Mikkelsen S, Svane O, Lynge E. Reporting of occupational cancer in Denmark. Scand J Work Environ Health 1990;16:401-5] Sino-nasal cancer is associated with occupational exposure to nickel (refining), wood dusts (furniture making), boot and shoe dusts (manufacturing), hexavalent chromium (pigment manufacturing), and radium (dial painting). [Ward, p. 366] Strong evidence: Boot and shoe manufacture and repair; furniture and cabinet making; isopropanol manufacture, strong acid process (sulfuric acid); nickel refining (nickel oxides and sulfides); wood dust. Suggestive evidence: chromium compounds, hexavalent; formaldehyde; mineral oils, untreated and mildly treated. [Siemiatycki, p. 334] |
Latency/Incubation |
Years to decades |
Diagnostic |
Biopsy |
ICD-9 Code |
160.0 |
|
|
Related Information in Haz-Map |
Agents |
Hazardous agents that cause the occupational disease:
|
|
|