[TPM Membership Roster] [TPM Meeting Rosters]

The Tumor Progression and Metastasis [TPM] Study Section reviews grant applications that deal with the basic mechanisms of cancer progression, metastasis, invasion/migration and angiogenesis.  Special emphasis is placed on hypoxia, inflammation, tumor imaging and pathology, adhesion, and growth.  Studies focusing on cytoskeleton, proteases, wound healing, extracellular matrix remodeling, suppressors/inhibitors of metastasis & angiogenesis, and animal models of metastasis & angiogenesis will also be assigned to this study section.  Specific areas covered by TPM:

• Transcriptional, posttranscriptional, translational and posttranslational regulation of tumor metastasis and angiogenesis including role of microRNA (miRNA), small inhibitory RNA (siRNA), short hairpin RNA (shRNA), small activating RNA (saRNA), ubiquitination, acetylation, and phosphorylation
• Tumor cell adhesion, invasion/migration, and angiogenesis including angiogenic factors and their receptors.
• Role of stress in tumor metastasis & angiogenesis including the function of hypoxia and inflammation
• In vitro and in vivo models of tumor metastasis and angiogenesis including genetics and imaging analysis
• Contribution of carbohydrate modifications, wound healing, and cell membrane specializations (e.g., caveolae and lipid rafts) as they relate to tumor invasion
• Role of stem cells in tumor metastasis and angiogenesis

The study sections with most closely related areas of similar science listed in rank order are:

Tumor Microenvironment Study Section [TME] 
Tumor Cell Biology Study Section [TCB] 
Cancer Molecular Pathobiology Study Section [CAMP] 
Basic Mechanisms of Cancer Therapeutics Study Section [BMCT] 
Intercellular Interactions Study Section [ICI]