Bioengineering Sciences and Technologies Small Business Activities [SBIR/STTR] Special Emphasis Panels

The Bioengineering Sciences and Technology IRG reviews small business applications within all of the research areas covered in our regular study sections, plus the additional areas highlighted below.  Some SBIR/STTR applications are reviewed in the context of regular study sections [Instrumentation and Systems Development [ISD], Biodata Management and Analysis [BDMA], Modeling and Analysis of Biological Systems [MABS], Microscopic Imaging [MI]], whereas other SBIR/STTR applications are reviewed in one of the following four special emphasis panels: 

 

 

Delivery Systems and Nanotechnology SBIR/STTR SEP [DSN SEP - BST (10)]

 

[BST (10) Roster]

 

The Delivery Systems and Nanotechnology SBIR/STTR SEP reviews small business applications in the general areas of new strategies, devices, vectors, and agents for delivering genes or drugs into cells or organisms. 

 

 

Specific areas covered by the DSN SEP include:

  • Viral and nonviral vectors for gene delivery

  • Genetic expression systems

  • Loaded nanomaterials, time release formulations, and other delivery vehicles

  • Devices and instrumentation for gene and drug delivery

  • Manufacturing processes for production of delivery vectors or vehicles

  • Initial testing of devices, vectors or vehicles in cellular and animal models

 

The DSN SEP shares the following interests within the BST IRG:

  • With the Materials Science and Environmental Monitoring SEP [MSEM SEP - BST (11)]: The Delivery Systems and Nanotechnology SBIR SEP shares interests with the MSEM SBIR SEP in the development of nanoparticles and other nano-scale materials.  If the emphasis is on the development of nano-scale materials and their initial testing in vivo, including cellular and/or animal systems, then assignment to the DSN SEP may be appropriate.  If the emphasis is on the development of nanomaterials and their initial testing in vitro, including cell lines, then assignment to the MSEM SEP may be appropriate.

  • With the Devices and Detection Systems SEP [DDS SEP - BST (12)]: The Delivery Systems and Nanotechnology SEP shares interests with the DDS SEP in the development of devices and instrumentation.  If the emphasis is on the development of devices and instrumentation for delivering genes and drugs into cells and organisms, then assignment to the DSN SEP may be appropriate.  If the emphasis is on the development of devices and instrumentation for application in other biomedical, pharmaceutical, or research settings, then assignment to the DDS SEP may be appropriate.

  • With the Assays and Methods Development SEP [AMD SEP - BST (13)]:  The Delivery Systems and Nanotechnology SEP shares interests with the AMD SEP in the development of devices, vectors, and vehicles for delivering genes and drugs into cells and organisms; monitoring the activities of the delivered agents; and manufacture of pharmaceutical-grade delivery vectors.  If the emphasis is on development of instrumentation and agents on a small scale or testing them in cellular or animal models, then assignment to the DSN SEP may be appropriate.  If the emphasis is on development or scale-up of instrumentation and agents on a large scale, then assignment to the AMD SEP may be appropriate.

  • With the Microscopic Imaging Study Section [MI]: The Delivery Systems and Nanotechnology SEP shares interests with the MI study section in the development of imaging instrumentation and genetic reporter systems.  If the emphasis is on the development of imaging instrumentation and genetic reporter systems for use in monitoring the efficiency or activity of genes or drugs delivered for an eventual therapeutic purpose, then assignment to the DSN SEP may be appropriate.  If the emphasis is on the development of imaging instrumentation and genetic reporter systems for use in visualizing the activities of cells or molecules to address a biological or biomedical question, then assignment to the MI study section may be appropriate.



The DSN SEP shares the following interests outside the BST IRG:

  • With the Biological Chemistry and Macromolecular Biophysics [BCMB] IRGThe Delivery Systems and Nanotechnology SEP shares interests with the BCMB IRG in the formulation and synthesis of new materials and vehicles.  If the emphasis is on the development of new materials and vehicles for delivering agents into cells or organisms, or to elucidate engineering principles, then assignment to the DSN SEP may be appropriate.  If the emphasis is on the development of new materials and vehicles to elucidate biochemical or biophysical principles, or on the application of existing technologies to biochemical or biophysical problems, then assignment to the BCMB IRG may be appropriate.

  • With the Genes, Genomes, and Genetics [GGG] IRG: The Delivery Systems and Nanotechnology SEP shares interests with the GGG IRG in the area of gene therapy.  If the emphasis is on the development and initial testing of delivery devices, vectors and vehicles, even if their eventual intended use is gene therapy, or to elucidate engineering principles, then assignment to the DSN SEP may be appropriate.  If the emphasis is on the use of existing devices, vectors, or vehicles to ameliorate an inborn error, then assignment to the GGG IRG may be appropriate.

  • With the Oncological Sciences [ONC] IRG: The Delivery Systems and Nanotechnology SEP shares interests with the ONC IRG in the development of devices, vectors, or vehicles for delivering genes and drugs.  If the emphasis is on the development and initial testing of new technology for delivering genes and drugs into cells or biological systems, including tumors, or to elucidate engineering principles, then assignment to the DSN SEP may be appropriate.  If the emphasis is on the application of existing technology for delivering genes and drugs into tumors and monitoring therapeutic results, or for elucidating biological mechanisms related to oncology or therapeutics, then assignment to the ONC IRG may be appropriate.

  • With the Surgical Sciences, Biomedical Imaging, and Bioengineering [SBIB] IRG: The Delivery Systems and Nanotechnology SEP shares interests with the SBIB IRG in the area of anesthesiology and drug delivery.  If the emphasis is on the development of new delivery systems and their initial testing in cellular or animal systems, then assignment to the DSN SEP may be appropriate.  If the emphasis is on the application of existing technology or testing of new technologies in clinical/surgical settings, then assignment to the SBIB IRG may be appropriate.
     

 

       

Materials Science and Environmental Monitoring SBIR/STTR SEP [MSEM SEP - BST (11)]

 

[BST (11) Roster]

 

The Materials Science and Environmental Monitoring SBIR/STTR SEP reviews small business applications in the general areas of new surfaces, coatings, and materials, and technology for environmental and biodefense purposes. 

 

 

Specific areas covered by the MSEM SEP include:

  • Biosensors, chips, and other platforms for detecting chemicals, toxins, and pathogens in the environment or workplace

  • Materials, coatings, and surfaces for use in gene and drug delivery, medical devices and implants, biosensors, detectors, and manufacturing settings

  • Nano-scale materials, nanoparticles, and surface phenomena

  • Tissue engineering, cell/scaffold interactions, cellular assays of toxicity and tolerance

  • Platforms, devices, and manufacturing practices for reducing chemicals, toxins, and pathogens in the environment or workplace

 

The MSEM SEP shares the following interests within the BST IRG:


  • With the Delivery Systems and Nanotechnology SEP [DSN SEP - BST (10)]: The Materials Science and Environmental Monitoring SEP shares interests with the DSN SEP in the development of devices and instrumentation.  If the emphasis is on the development of devices and instrumentation for use in the environment, workplace, or industrial setting, then assignment to the MSEM SEP may be appropriate.  If the emphasis is on the development of devices and instrumentation for delivering genes and drugs into cells and organisms, then assignment to the DSN SEP may be appropriate.

  • With the Devices and Detection Systems SEP [DDS SEP - BST (12)]: The Materials Science and Environmental Monitoring SEP shares interests with the DDS SEP in the development of instrumentation and detection technology.  If the emphasis is on development of devices or instrumentation for use in the environment, workplace, or industrial setting, then assignment to the MSEM SEP may be appropriate.  If the emphasis is on development of devices or instrumentation for use in the biomedical, pharmaceutical, or research setting, then assignment to the DDS SEP may be appropriate.

  • With the Assays and Methods Development SEP [AMD SEP - BST (13)]: The Materials Science and Environmental Monitoring SEP shares interests with the AMD SEP in the development of assays and materials.  If the emphasis is on the development of assays and materials for screening the environment, workplace, or industrial setting, then assignment to the MSEM SEP may be appropriate.  If the emphasis is on development of assays and materials for screening in the biomedical, pharmaceutical or research setting, then assignment to the AMD SEP may be appropriate.

 

The MSEM SEP shares the following interests outside  the BST IRG:

  • With the Biological Chemistry and Macromolecular Biophysics [BCMB] IRG: The Materials Science and Environmental Monitoring SEP shares interests with the BCMB IRG in the areas of materials science and biosensors.  If the emphasis is on the development of new materials or biosensors for use in biomedical, pharmaceutical, or research settings, or to elucidate engineering principles, then assignment to the MSEM SEP may be appropriate.  If the emphasis is on elucidation of biophysical or biochemical principles that may be used to understand materials or to develop biosensors, or on the application of existing technology to biophysical research problems, then assignment to the BCMB IRG may be appropriate.

  • With the Surgical Sciences, Biomedical Imaging, and Bioengineering [SBIB] IRG: The Materials Science and Environmental Monitoring SEP shares interests with the SBIB IRG in the area of medical devices, medical sensors, and implants.  If the emphasis is on the development of new coatings, surfaces, or materials for eventual use in medical devices, sensors, or implants, or to elucidate basic bioengineering principles, then assignment to the MSEM SEP may be appropriate.  If the emphasis is on the application or testing of existing coatings, surfaces, or materials in medical devices, sensors, or implants, or to elucidate bioengineering principles related to clinical applications, then assignment to the SBIB IRG may be appropriate.

     
 
  

Devices and Detection Systems SBIR/STTR SEP

[DDS SEP: BST (12)]

 

[BST (12) Roster]

 

The Devices and Detection Systems SBIR/STTR SEP reviews small business applications in the general area of instrumentation and systems development, and related engineering principles.

 

Specific areas covered by the DDS SEP include:
 

  • Chips, microarrays, and other platforms for molecular separations and screens, immunoassays, chemical reactions, and molecular detection

  • Non-invasive biosensors for detecting or measuring drugs or other analytes in bodily fluids

  • Portable devices for point-of-care use, first response, or field monitoring

  • Microfluidic, nanofluidic, and robotic systems

  • Detectors and signal capture systems for use in instrumentation, molecular screens, and immunoassays

  • Power supplies, battery design, and other electrochemical devices

The DDS SEP shares the following shared interests within the BST IRG:

  • With the Delivery Systems and Nanotechnology SEP [DSN SEP - BST (10)]: The Devices and Detection Systems SEP shares interests with the DSN SEP in the development of devices and instrumentation.  If the emphasis is on the development of devices and instrumentation for delivering genes and drugs into cells and organisms, then assignment to the DSN SEP may be appropriate.  If the emphasis is on the development of devices and instrumentation for application in other biomedical, pharmaceutical, or research settings, then assignment to the DDS SEP may be appropriate.

  • With the Materials Science and Environmental Monitoring SEP [MSEM SEP - BST (11)]: The Devices and Detection SEP shares interests with the DDS SBIR SEP in the development of detection technology and instrumentation.  If the emphasis is on development of devices or instrumentation for use in the environment, workplace, or industrial setting, then assignment to the MSEM SEP may be appropriate.  If the emphasis is on development of devices or instrumentation for use in biomedical, pharmaceutical, or research settings, then assignment to the DDS SEP may be appropriate.

  • With the Assays and Methods Development SEP [AMD SEP - BST (13)]: The Devices and Detection SEP shares interests with the AMD SEP in the development of chips, sensors, platforms, and detectors.  If the emphasis is on development of these devices for use in small-scale settings, then assignment to the DDS SEP may be appropriate.  If the emphasis is on development of these devices for use in large-scale or high throughput settings, then assignment to the AMD SEP may be appropriate. 

 

The DDS SEP shares the following interests outside of the BST IRG:

  • With the Biological Chemistry and Macromolecular Biophysics [BCMB] IRG: The Devices and Detection Systems SEP shares interests with the BCMB IRG in the area of instrumentation technology.  If the emphasis is on the development of new instrumentation to detect or measure a specific molecule or analyte, or to elucidate engineering principles, then assignment to the DDS SEP may be appropriate.  If the emphasis is on the development of instrumentation for elucidating biochemical or biophysical principles, or the application of existing instrumentation to biochemical or biophysical problems, then assignment to the BCMB IRG may be appropriate.
  • With the Surgical Sciences, Biomedical Imaging, and Bioengineering [SBIB] IRG: The Devices and Detection Systems SEP shares interests with the SBIB IRG in the area of instrumentation development.  If the emphasis is on the development of non-invasive, hand-held, or portable instrumentation, even if intended for eventual use in clinical or health care settings, or to elucidate basic bioengineering principles, then assignment to the DDS SEP may be appropriate.  If the emphasis is on the development of instrumentation for use in surgery, medical implantation, or other clinical applications, then assignment to the SBIB IRG may be appropriate.

    

 

Assays and Methods Development SBIR/STTR SEP 

[AMD SEP - BST (13)]

 

[BST (13) Roster]

 

The Assays and Methods Develop SBIR/STTR SEP reviews small business applications in the general areas of high throughput (HTP) molecular assays, large-scale reactions, and HTP screening. 

 

Specific areas covered by the AMD SEP include:


  • Reporter systems for monitoring molecular interactions, drug candidates, and molecular or cellular activity

  • Chips, microarrays, biosensors, and other HTP platforms

  • Instrumentation, fluidics, and robotics for HTP assays or large-scale screens

  • Large-scale assays for genomic, proteomic, and metabolomic stud ies

  • Large-scale synthesis of biological molecules or drugs

  • Technology for the manufacture of biological molecules or drugs, including production and purification of recombinant proteins or designer molecules

  • Synthetic biology

 

 

The AMD SEP has the following shared interests within the BST IRG:

  • With the Delivery Systems and Nanotechnology SBIR/STTR SEP [DSN BST (10)]: The Assays and Methods Development SBIR/STTR SEP shares interests with the DSN SEP in the development of devices, vectors, and vehicles for delivering genes and drugs into cells and organisms; monitoring the activities of the delivered agents; and manufacture of pharmaceutical-grade delivery vectors.  If the emphasis is on the large-scale development or scale-up of devices, vectors, and vehicles, then assignment to the AMD SEP may be appropriate.  If the emphasis is on development of devices, vectors, or vehicles on a small scale or testing them in cellular or animal models, then assignment to the DSN SEP may be appropriate.

  • With the Materials Science and Environmental Monitoring SBIR/STTR SEP [MSEM BST (11)]: The Assays and Methods Development SBIR/STTR SEP shares interests with the MSEM SEP in the development of surfaces, coatings, and materials, as well as assays, biosensors, platforms, and methods.  If the emphasis is on the development of technology for use in the biomedical, pharmaceutical, or research setting or manufacture, then assignment to the AMD SEP may be appropriate.  If the emphasis is on the development of technology for use in environmental science, occupational safety, or biodefense, then the MSEM SEP may be appropriate.

  • With the Devices and Detection Systems SEP [DDS BST (12)]: The Assays and Methods Development SEP shares interests with the DDS SEP in the development of chips, sensors, platforms, and detectors.  If the emphasis is on the development of these devices for use in large-scale or HTP science, then assignment to the AMD SEP may be appropriate. If the emphasis is on the development of these devices for use in small-scale settings, then assignment to the DDS SEP may be appropriate.

  • With the Microscopic Imaging study section [MI]: The Assays and Methods Development SEP shares interests with the MI study section in the development of imaging technology to monitor cellular or molecular activity.  If the emphasis is on the development of imaging technology for use in large-scale or HTP settings, then assignment to the AMD SEP may be appropriate.  If the emphasis is on the development of imaging technology for use in small-scale settings, then assignment to the MI study section may be appropriate.

       

The AMD SEP has the following shared interests outside the BST IRG: 

  • With the Biological Chemistry and Macromolecular Biophysics [BCMB] IRG: The Assays and Methods Development SEP shares interests with the BCMB IRG in tools and instrumentation, and in drug discovery and development.  If the emphasis is on technology development or elucidating engineering principles, then assignment to the AMD SEP may be appropriate.  If the emphasis is on elucidating biochemical or biophysical principles for use in developing new tools, instrumentation, or drug discovery, or on the application of existing technology to these problems, then assignment to the BCMB IRG may be appropriate.

  • With the Cell Biology [CB] IRG: The Assays and Methods Development SEP shares interests with the CB IRG in assays and systems for monitoring cellular activity.  If the emphasis is on technology development for use in high throughput settings, monitoring a variety of biological activities, or elucidating engineering principles, then assignment to the AMD SEP may be appropriate.  If the emphasis is on the development of systems to address individual questions related to cell biology, or application of existing technology to individual research problems, then assignment to the CB IRG may be appropriate.

  • With the Genes, Genomes, and Genetics [GGG] IRG: The Assays and Methods Development SEP shares interests with the GGG IRG in technology for genomic studies.  If the emphasis is on technology development, HTP settings, or elucidating engineering principles, then assignment to the AMD SEP may be appropriate.  If the emphasis is on the application of existing technology to individual research problems, or elucidating genetic principles or the genome, then assignment to the GGG IRG may be appropriate.

 



 

       

       



    Home | Contact CSR | Staff Directory | Site Map | FOIA | Disclaimer & Privacy Statements | Accessibility Statement
    Last updated: November 19, 2008

    National Institutes of Health National Institutes of Health   Department of Health and Human Services Department of Health and Human Services USA.gov Government Made Easy