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Home » Study Results & Research Projects » NTP Study Reports » AIDS Therapeutics Toxicity Studies Program
Infection with human immunodeficiency virus (HIV) causes immunosuppression and leads to acquired immunodeficiency syndrome (AIDS) with a broad spectrum of opportunistic infections. Prophylaxis and treatment of AIDS are generally combination therapies of antiretroviral agents with antimicrobial drugs specific for the opportunistic infections. The National Institute of Environmental Health Sciences (NIEHS), under the AIDS research program, collaborates with other institutes of the NIH, other government agencies, and pharmaceutical companies to evaluate the reproductive/developmental toxicity, general toxicity, immunotoxicity and neurotoxicity of AIDS therapeutics. These evaluations may include single therapeutic agents or combination therapies when the toxic potential of these agents in animal models is not available or is incomplete. The studies with combination therapies are very important in that they will increase awareness and understanding of interactions between antiretroviral therapies and other drugs/substances that HIV-infected individuals may be using.
NIEHS AIDS Therapeutics Toxicity Reports:
AIDS Publication Abstracts:
To receive printed copies of these documents or publications, contact Central Data Management
Links to other AIDS Information Sites
National Institute of Allergy and Infectious Diseases - Division of Acquired Immune Deficiency Syndrome
The National Library of Medicine - AIDS Information Resources
Report of the NIH AIDS Research Program Evaluation Working Group -- Office of AIDS Research Advisory Council
Department of Veterans Affairs -- AIDS Research Center
Web page last updated on January 04, 2007
The National Institute of Environmental Health Sciences is one of the National Institutes of Health within the U.S. Department of Health and Human Services. The National Toxicology Program is headquartered on the NIEHS campus in Research Triangle Park, NC.