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UC-781
Drug Class: Microbicides
UC-781 is a type of medicine called a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is being studied as a microbicide. Microbicides are substances that protect the body from infection by microorganisms such as bacteria, viruses, and fungi. NNRTIs block reverse transcriptase, a protein that HIV needs to make more copies of itself. Microbicides work by either destroying the microbes or preventing them from establishing an infection.

HIV/AIDS-Related Uses
UC-781 is an investigational medicine that is not yet approved by the FDA for use outside of clinical trials. It is being studied for the prevention of sexual transmission of HIV infection. This medicine does not cure HIV infection or AIDS and is being studied to reduce the risk of passing the virus to other people.

Dosage Form/Administration
UC-781 comes in a topical gel form and is applied vaginally.

Contraindications
Individuals should tell a doctor about any medical problems before taking this medicine.

Possible Side Effects
Along with its desired effects, UC-781 may cause some unwanted effects. UC-781 has not yet been fully studied in clinical trials, so these effects are not yet known. In laboratory studies, UC-781 was not harmful to human tissue samples.

Drug and Food Interactions
A doctor should be notified of any other medications being taken, including prescription, non-prescription (over-the-counter), or herbal medications.

Clinical Trials
Click here to search ClinicalTrials.gov for trials that use UC-781.

Manufacturer Information
UC-781
  Cellegy Pharmaceuticals, Inc
  3490 Oyster Point Boulevard
  Suite 200
  South San Francisco,  CA  94080
  (650) 616-2200
    
Updated February 12, 2008