Structure and Function of the Immunological Synapse

 


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Air date: Wednesday, September 17, 2008, 4:15:00 PM
Category: Immunology
Description: Andrey is interested in how T cells and NK cells recognize their targets and how this recognition event is translated into an appropriate immunological response. He combines biochemical and genetic analyses with modern imaging methods, which are essential to understand signaling at the single cell level. His work has revealed important features of the immunological synapse, such as T cell receptor signaling prior to synapse formation, and T cell receptor internalization at the center of the synapse. He is using mathematical modeling to develop hypotheses about the role of the synapse in controlling the strength of signals. Andrey is an entertaining speaker, not afraid to challenge established views.

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The Immunology Interest Group
Author: Andrey Shaw, M.D.
Runtime: 62 minutes
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CIT File ID: 14649
CIT Live ID: 7075
Permanent link: http://videocast.nih.gov/launch.asp?14649