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Stroke Diagnostics and Therapeutics Section
Steven Warach, M.D., Ph.D., Senior Investigator
Dr. Warach received his B.S., M.A. and Ph.D. degrees from Michigan State University and his M.D. degree from Harvard Medical School. After receiving his PhD in neuroscience and psychology for studies of cerebrovascular effects of cognitive tasks and gender, he did his postdoctoral work at the University of Pennsylvania in Dr. Martin Reivich's Cerebrovascular Research Center. Upon completion of his MD, he did his neurology residency in the Harvard-Longwood Neurology Training Program. In conjunction with his residency, Dr. Warach completed an MRI Fellowship with Dr. Robert Edelman at Beth Israel Hospital in Boston, MA. During this fellowship he began his work developing and using diffusion-perfusion MRI methods for the clinical diagnosis, management and investigation of acute stroke. In 1993 he joined the faculty of the Neurology Department at Beth Israel Hospital, and in 1994 he was appointed Chief of the Division of Cerebrovascular Diseases. Dr. Warach joined NINDS in 1999 as Chief of the newly formed Section on Stroke Diagnostics and Therapeutics. Dr. Warach's section will be identifying promising experimental stroke therapies through the use of imaging surrogate markers.
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Staff:
- Dr. Li An, Ph.D., Staff Scientist, 301-896-2882 anl@ninds.nih.gov
- Taura Barr, R.N., Graduate Student, 301-896-7547 barrt@ninds.nih.gov
- Ayush Batra, HHMI Scholar, 301-435-8883 batraay@mail.nih.gov
- Dr. Tanya Bogoslovsky, Visiting Fellow, 301-435-8094 bogoslovskyt@ninds.nih.gov
- Dr. Krishna Dani, Special Volunteer, 202-877-3124 danika@ninds.nih.gov
- Lisa Davis, R.N., Nurse, 301-435-7659 davisl@ninds.nih.gov
- Dr. Erica Henning, Ph.D., Postdoctoral Fellow, 301-435-1929 henninge@ninds.nih.gov
- Ms. Lizbeth Keller, B.S., Research Associate, 202-877-3118 kellerli@ninds.nih.gov
- Katherine Ku, B.S., Postbaccalaureate IRTA, 301-402-9039 kuk2@ninds.nih.gov
- Dr. Lawrence Latour, Ph.D., Staff Scientist, 301-496-0463 latourl@ninds.nih.gov
- Ms. Shoshanna Levine, Research Assistant, 301-896-2944 levinesh@ninds.nih.gov
- Dr. Marie Luby, Ph.D., Contractor, 301-435-3002 lubym@ninds.nih.gov
- Patricia Lyall, Program Specialist, 301-435-2395 lyallp@ninds.nih.gov
- Dr. John Lynch, D.O., Staff Clinician, 301-896-7547 lynchj@mail.nih.gov
- Ashleigh Martin, B.S., Postbaccalaureate IRTA, 301-435-9321 martinash@ninds.nih.gov
- Xi Sheng, Pre-doctoral IRTA, 301-435-2935 shengx@ninds.nih.gov
- Leslie Shupenko, B.S., M.S, Contractor, 202-877-4019 shupenkol@ninds.nih.gov
- Dr. Shlee Song, Clinical Fellow, 301-435-9321 songs3@ninds.nih.gov
- Ms. Elizabeth Tedrow, Research Assistant, 202-877-8182 tedrowe@ninds.nih.gov
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Research Interests:
1) Develop and assess novel imaging methods in the care of stroke patients; 2) Evaluate novel stroke therapeutic strategies; 3) Investigate human stroke pathophysiology; 4) Develop and validate MRI as a surrogate marker in drug development for stroke.
Clinical Protocols:
- Evaluation, Pathogenesis and Treatment of Patients with Cerebrovascular Disease 01-N-0007
- CATALIST - Combination Anti-platelet and Anti-coagulation Treatment After Lysis of Ischemic Stroke Trial 03-N-0171
Selected Publications:
- Chalela J, Kidwell C, Nentwich L, Butman J, Demchuk A, Hill M, Patronas N, Latour LL, Warach S (2007) Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison , The Lancet 369, 293-298.
- Kang DW, Chalela JA, Dunn W, Warach S (2005) MRI screening prior to standard tPA therapy is feasible and safe, Stroke 36, 1939-1943.
- Latour LL, Kang DW, Ezzeddine MA, Chalela JA, Warach S (2004) Early blood brain barrier disruption in human focal brain ischemia, Annals of Neurology 56(4), 468-477. Full Text/Abstract
- Kidwell CS, Chalela JA, Saver JL, Starkman S, Hill MD, Demchuk AM, Butman JA, Patronas N, Alger JR, Latour LL, Luby ML, Baird AE, Leary MC, Tremwel M, Ovbiagele B, Fredieu A, Suzuki S, Villablanca JP, Davis S, Dunn B, Todd JW, Ezzeddine MA, Haymore J, Lynch JK, Davis U, Warach S (2004) Comparison of MRI and CT for detection of acute intracerebral hemorrhage, JAMA 292 (15), 1823-1830. Full Text/Abstract
- Bykowski JL, Latour LL, Warach S (2004) More accurate identification of reversible ischemic injury in human stroke by cerebrospinal fluid suppressed diffusion-weighted imaging., Stroke 35(5), 1100-6. Full Text/Abstract
- Chalela JA Kang DW Luby M Ezzeddine M Latour LL Todd JW Dunn B Warach S (2004) Early magnetic resonance imaging findings in patients receiving tissue plasminogen activator predict outcome: Insights into the pathophysiology of acute stroke in the thrombolysis era. , Ann Neurol 55 , 105-12 . Full Text/Abstract
- Kang DW Latour LL Chalela JA Dambrosia J Warach S (2003) Early ischemic lesion recurrence within a week after acute ischemic stroke. , Ann Neurol 54 , 66-74 . Full Text/Abstract
All Selected Publications
Contact Information:
Dr. Steven Warach
Stroke Diagnostic and Therapeutic Section
Stroke Branch, NINDS
Building 10, Room B1D733
10 Center Drive, MSC 1063
Bethesda, MD 20892-1063
Telephone: 301-435-9321 office,
301-435-9321 laboratory,
301-480-0413 fax
Email: warachs@ninds.nih.gov
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