Haz-Map: Occupational Exposure to Hazardous Agents

Related Information in Haz-Map
Disease/Syndrome	Omsk hemorrhagic fever
Category	Infection, Occupational
Acute/Chronic	Acute-Severe
Synonyms	OHF
Biomedical References	Search PubMed
Comments	This disease is similar to Kyasanur forest disease. In severe cases, mucous membrane, gastrointestinal, and uterine hemorrhages occur. A 1% to 10% case-fatality rate is estimated. OHF is transmitted by ticks; it is also transmitted directly from muskrats to muskrat trappers and their families. A vaccine is available, but its effectiveness has not been proven. [CCDM, p. 54-5] Other symptoms are cough, conjunctivitis, and splenomegaly. Pneumonia and CNS dysfunction are complications. [JAMA.2002;287:2391-2404]
Latency/Incubation	3-8 days
Diagnostic	Viral culture; Paired sera
ICD-9 Code	065.1
Available Vaccine	Yes
Scope	Western Siberia within the Omsk, Novosibirsk, Kurgan and Tjumen regions;
Reference Link	Health Canada - Omsk Hemorrhagic Fever
Symptoms/Findings	Symptoms/Findings associated with this disease: bleeding diathesis blood in stool conjunctivitis, acute cough diarrhea epistaxis fatigue fever headache hematemesis leukopenia limb pain low back pain lymphadenopathy nausea, vomiting petechiae and ecchymoses shock splenomegaly stomatitis thrombocytopenia
Job Tasks	High risk job tasks associated with this disease: Handle infected rodents (inhalation or percutaneous exposure) Travel to endemic area with inadequate protection Work in a medical or research laboratory handling the pathogen Work in tick infested area