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Disease/Syndrome Laryngeal cancer
Category Cancer, Occupational
Acute/Chronic Chronic
Synonyms Cancer of larynx; Laryngeal cancer; Larynx neoplasms; Larynx cancer; Laryngeal neoplasms
Biomedical References Search PubMed
Comments In western countries, cancer of the larynx is for the most part attributable to smoking tobacco and drinking alcohol. Possible occupational risks include exposure to nickel, asbestos, and ionizing radiation. [Adami, p. 271] Studies of cohorts from past decades have found strong associations between laryngeal cancer and occupational exposures to mustard gas manufacturing, nickel refining, and metalworking with mineral-based oils. [Ward, p. 296] Risk factors for laryngeal cancer include smoking, drinking alcohol, and asbestos exposure. Possible risk factors are leather workers, textile workers, and exposure to gasoline, diesel oil, and mineral oil. [LaDou, p. 302-3] There is strong evidence that the following are occupational carcinogens: isopropanol manufacture, strong acid process; inorganic acid mists containing sulfuric acid; and mustard gas. There is suggestive evidence that exposure to asbestos and the rubber industry are associated with an increased risk of work-related laryngeal cancer. [Siemiatycki, p. 334] "The committee concluded that the evidence is sufficient to infer a causal relationship between asbestos exposure and laryngeal cancer." [National Academy of Sciences. Asbestos: Selected Cancers. 2006]
Latency/Incubation Years to decades
Diagnostic Biopsy
ICD-9 Code 161
Reference Link IARC: Mists of sulfuric acid and other strong inorganic acids
Related Information in Haz-Map
Agents Hazardous agents that cause the occupational disease:





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Last updated: September, 2008