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Agent Name Bisphenol A
Alternative Name 4,4'-Isopropylidenediphenol
CAS Number 80-05-7
Formula C15-H16-O2
Major Category Plastics & Rubber
Synonyms 2,2-(4,4'-Dihydroxydiphenyl)propane; 2,2-Bis(4-hydroxyphenyl)propane; 2,2-Bis(hydroxyphenyl)propane; 2,2-Bis(p-hydroxyphenyl)propane; 2,2-Bis-4'-hydroxyfenylpropan [Czech]; 2,2-Di(4-hydroxyphenyl)propane; 2,2-Di(4-phenylol)propane; 4,4'-(1-Methylethylidene)bisphenol; 4,4'-Bisphenol A; 4,4'-Dihydroxydiphenyl-2,2-propane; 4,4'-Dihydroxydiphenyldimethylmethane; 4,4'-Dihydroxydiphenylpropane; 4,4'-Isopropylidene diphenol; 4,4'-Isopropylidenebisphenol; 4,4'-Isopropylidenediphenol; Biphenol A; Bis(4-hydroxyphenyl) dimethylmethane; Bis(4-hydroxyphenyl)dimethylmethane; Bis(4-hydroxyphenyl)propane; Bisferol A [Czech]; Bisphenol; Bisphenol A; Bisphenol-A; DIAN; Diano; Dimethyl bis(p-hydroxyphenyl)methane; Dimethylbis(p-hydroxyphenyl)methane; Dimethylmethylene-p,p'-diphenol; Diphenylolpropane; Ipognox 88; Isopropylidenebis(4-hydroxybenzene); Parabis A; Phenol, (1-methylethylidene)bis-; Phenol, 4,4'-(1-methylethylidene)bis-; Phenol, 4,4'-dimethylmethylenedi-; Phenol, 4,4'-isopropylidenedi-; Pluracol 245; Propane, 2,2-bis(p-hydroxyphenyl)-; Rikabanol; Ucar bisphenol A; Ucar bisphenol HP; beta,beta'-Bis(p-hydroxyphenyl)propane; beta-Di-p-hydroxyphenylpropane; p,p'-Bisphenol A; p,p'-Dihydroxydiphenyldimethylmethane; p,p'-Dihydroxydiphenylpropane; p,p'-Isopropylidenebisphenol; p,p'-Isopropylidenediphenol; [ChemIDplus]
Category Epoxy Resins
Description White crystalline solid or flakes with a mild phenolic odour; [CHEMINFO]
Sources/Uses Used as a chemical intermediate, mainly for epoxy resins and polycarbonate resins; [HSDB] Used with epichlorohydrin to produce bisphenol-A diglycidyl ether, the monomer in bisphenol-A type epoxy resins; [Kanerva, p. 1132]
Comments A skin, eye, and respiratory tract irritant; "Repeated or prolonged contact may cause skin sensitization." [ICSC] Reported, but controversial, cause of allergic contact dermatitis in epoxy resin workers; [Kanerva, p. 1132]
Reference Link Occupational allergic contact dermatitis caused by epoxy diacrylate in ultraviolet-light-cured paint, and bisphenol A in dental composite resin
Exposure Assessment
Skin Designation (ACGIH) Not evaluated
MAK 5 mg/m3, inhalable fraction
Vapor Pressure 3.91 x 10 -07 mm Hg
Lethal Concentration LC (mice) > 1,700 mg/m3/2h; (inhalation)
Explanatory Notes Flash point = 175 deg F;
Reference Link International Chemical Safety Cards (WHO/IPCS/ILO)
Adverse Effects
Skin Sensitizer Yes
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: 4,4'-BISPHENOL A  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





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Last updated: September, 2008