| Agent Name |
Hexamethylene tetramine |
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| CAS Number |
100-97-0 |
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| Formula |
C6-H12-N4 |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
1,3,5,7-Tetraazaadamantane; 1,3,5,7-Tetraazatricyclo (3.3.1.1(3,7))decane; 1,3,5,7-Tetraazatricyclo(3.3.1.1(sup 3,7))decane; 1,3,5,7-Tetraazatricyclo(3.3.1.1(sup 37))decane; Aceto HMT; Aminoform; Aminoformaldehyde; Ammoform; Ammonioformaldehyde; Antihydral; Cystamin; Cystogen; Duirexol; Ekagom H; Esametilentetramina [Italian]; Formamine; Formin; Formin (heterocycle); HMT; Herax UTS; Heterin; Hexa (vulcanization accelerator); Hexa-Flo-Pulver; Hexaform; Hexaloids; Hexamethylenamine; Hexamethyleneamine; Hexamethylenetetraamine; Hexamethylenetetramine; Hexamethylenetetraminum; Hexamethylentetramin [German]; Hexamethylentetramine; Hexamethylentetraminum; Hexamine; Hexamine (heterocycle); Hexaminum; Hexasan; Hexasan (VAN); Hexilmethylenamine; Metenamina [INN-Spanish]; Methenamin; Methenamine; Methenaminum [INN-Latin]; Metramine; Nocceler H; Preparation AF; Resotropin; S 4 (heterocycle); Sanceler H; Uramin; Uratrine; Uritone; Urodeine; Urotropin; Urotropine; Vulkacit H 30; Xametrin; [ChemIDplus] UN1328 |
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| Category |
Amines, Aliphatic |
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| Description |
White, crystalline powder or colorless, lustrous crystals; [HSDB] |
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| Sources/Uses |
Used in adhesives, coatings, sealants, and leather preservatives; also used as an anticorrosion agent, antibiotic, dye fixative, chemical stabilizer, and curing agent for formaldehyde resins and rubber; [HSDB] Used as a drug (methenamine) taken by mouth to prevent recurrent urinary tract infections; [Medscape DrugInfo] Used as a hardener for epoxy resins of the bisphenol A type; [Kanerva, p. 1155] Used as a formaldehyde releaser for photographic film development. [Kanerva, p. 1054-5] |
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| Comments |
Decomposes into formaldehyde and can cause occupational asthma and skin sensitization; [ICSC] [Gelfand HH. Respiratory allergy due to chemical compounds encountered in the rubber, lacquer, shellac, and beauty culture industries. J Allergy 34:374-381, 1963. (Not in PubMed)] Merck Index # 5966; Allergic contact dermatitis reported in ceramics workers; [Kanerva, p. 1155] A skin and eye irritant; A skin sensitizer; May cause asthma; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Vapor Pressure |
0.004 mm Hg |
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| Explanatory Notes |
Flash point = 482 deg F; |
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| Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
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| Adverse Effects |
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| Asthma |
Yes |
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| Skin Sensitizer |
Yes |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: METHENAMINE
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