| Agent Name |
N,N-Dimethyl-1,3-propanediamine |
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| Alternative Name |
DMAPA |
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| CAS Number |
109-55-7 |
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| Formula |
C5-H14-N2 |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
1,3-Propanediamine, N,N-dimethyl-; 1-(Dimethylamino)-3-aminopropane; 1-Amino-3-dimethylaminopropane; 3-(Dimethylamino)-1-propanamine; 3-(Dimethylamino)-1-propylamine; 3-(Dimethylamino)propylamine; 3-Amino-1-(dimethylamino)propane; N,N-Dimethyl-1,3-diaminopropane; N,N-Dimethyl-1,3-propanediamine; N,N-Dimethyl-1,3-propylenediamine; N,N-Dimethyl-N-(3-aminopropyl)amine; N,N-Dimethylpropylenediamine; N,N-Dimethyltrimethylenediamine; N-Dimethyltrimethylenediamine; Propylamine, 3-(N,N-dimethylamino)-; gamma-(Dimethylamino)propylamine; [ChemIDplus] UN1993; UN2734 |
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| Category |
Amines, Aliphatic |
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| Description |
Colorless liquid; [HSDB] |
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| Sources/Uses |
Used as curing agent for epoxy resins and polyurethanes; used as chemical intermediate in the production of surface active agents for water treatment, motor oil additives, fabric softeners, etc. [HSDB] |
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| Comments |
Occupational asthma reported in workers manufacturing skis; [Malo] Allergic contact dermatitis has been reported in workers handling epoxy resins or using products containing cocamidopropyl betaine. DMAPA is a contaminant in such products and the responsible allergen. [Kanerva, p. 1146] A corrosive substance that can cause pulmonary edema; A skin sensitizer; [ICSC] |
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| Reference Link |
Respiratory effects of occupational exposure to an epoxy resin system |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Vapor Pressure |
9.75 mm Hg |
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| Odor Threshold Low |
0.1 ppm |
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| Explanatory Notes |
Vapor pressure at 30 degrees C = 1.33 kPa (9.75 mm Hg); [ICSC] Flash point = 90 deg F; Odor threshold from CHEMINFO; |
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| Reference Link |
3-Dimethylaminopropylamine: a key substance in contact allergy to cocamidopropylbetaine? |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Asthma |
Yes |
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| Toxic Pneumonitis |
Yes |
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| Dermatotoxin |
Skin Burns |
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| Skin Sensitizer |
Yes |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: N,N-DIMETHYL-1,3-PROPANEDIAMINE
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