| Agent Name |
N-Nitrosodi-n-propylamine |
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| Alternative Name |
NDPA |
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| CAS Number |
621-64-7 |
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| Formula |
C6-H14-N2-O |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
1-Propanamine, N-nitroso-N-propyl-; Di-n-propylnitrosamine; Di-n-propylnitrosoamine; Dipropylamine, N-nitroso-; Dipropylnitrosamine; N,N-Di-n-propylnitrosamine; N,N-Dipropylnitrosamine; N-Nitroso-N-propyl-1-propanamine; N-Nitrosodi-n-propylamine; N-Nitrosodipropylamine; Nitrosodipropylamine; Propanamine, N-nitroso-N-propyl-; Propylamine, N-nitroso-N-di-; [ChemIDplus] UN3077 |
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| Category |
Nitrosamines |
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| Description |
Yellow liquid; [HSDB] |
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| Sources/Uses |
Not produced in the United States; used primarily for research; [HSDB] "Small amounts of N-nitrosodi-n-propylamine are produced as a side reaction during some manufacturing processes, as a contaminant in some commonly available weed killers (dinitroaniline-based), and during the manufacture of some rubber products. When exposed to sunlight, N-nitrosodi-n-propylamine usually does not last for more than a day." [ATSDR ToxProfiles] |
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| Comments |
In animal experiments, N-nitrosodi-n-propylamine causes hepatic injury after acute exposure and cancer of the liver after chronic exposure. [ATSDR ToxProfiles] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Vapor Pressure |
0.08 mm Hg |
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| Explanatory Notes |
Carcinogen--No TLV; |
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| Reference Link |
ATSDR ToxFAQs - N-nitrosodi-n-propylamine |
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| Adverse Effects |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| IARC Carcinogen |
Possible Carcinogen |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: N-NITROSODI-N-PROPYLAMINE
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