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Agent Name Pentaborane
CAS Number 19624-22-7
Formula B5-H9
Major Category Toxic Gases & Vapors
Synonyms Pentaboron nonahydride; [NIOSH]
Category Hydrides
Description Colorless liquid with a pungent odor like sour milk; [NIOSH]
Sources/Uses Pentaborane has been used as a rocket fuel. [ACGIH]
Comments Workers accidentally exposed to pentaborane vapor experienced central nervous system effects at lower doses and tremors and seizures at higher doses. [ACGIH] A severe irritant of the eyes and respiratory tract; [ICSC] In one industrial accident with a fatality, patients had elevated liver enzymes and rhabdomyolysis. [HSDB] (Rhabdomyolysis is muscle tissue injury with release of myoglobin into the bloodstream and often kidney damage.)
Reference Link NIOSH: Occupational Health Guideline for Pentaborane
Exposure Assessment
Skin Designation (ACGIH) No
TIH Yes
TLV (ACGIH) 0.005 ppm
STEL (ACGIH) 0.01 ppm
PEL (OSHA) 0.005 ppm
MAK 0.005 ppm
IDLH (NIOSH) 1 ppm
Excerpts from Documentation for IDLHs Human data: None relevant for use in determining the revised IDLH.
Vapor Pressure 171 mm Hg
Odor Threshold Low 0.97 ppm
Lethal Concentration LC50 (rats) = 6 ppm/4H
Explanatory Notes Odor threshold from AIHA; Flash point = 86 deg F; Pyrophoric (Ignites upon contact with air;) [CHEMINFO]
Flammability (NFPA) 4: burns readily
Adverse Effects
Neurotoxin Other CNS Neurotoxin
Hepatotoxin Hepatotoxin, Secondary
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: PENTABORANE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





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Last updated: September, 2008