| Agent Name |
Phosphorus trichloride |
|---|
| CAS Number |
7719-12-2 |
|---|
| Formula |
Cl3-P |
|---|
| Major Category |
Toxic Gases & Vapors |
|---|
| Synonyms |
Fosforo(tricloruro di) [Italian]; Fosfortrichloride [Dutch]; Phosphine, trichloro-; Phosphore(trichlorure de) [French]; Phosphorous chloride; Phosphorous trichloride; Phosphortrichlorid [German]; Phosphorus chloride (Cl6P2); Phosphorus chloride (PCl3); Trichlorophosphine; Trojchlorek fosforu [Polish; [ChemIDplus] UN1809 |
|---|
| Category |
Other Toxic Gases & Vapors |
|---|
| Description |
Colorless to yellow, fuming liquid with an odor like hydrochloric acid; [NIOSH] |
|---|
| Sources/Uses |
Used to produce pesticides, gasoline additives, plasticizers, dyes, and textile-finishing agents; also used as a chlorine donor and catalyst in chemical reactions; [ACGIH] |
|---|
| Comments |
Liquid causes second or third degree burns after short contact; [CHRIS] Highly corrosive to skin; [Quick CPC] Rats develop nephrosis and pulmonary edema after 4 hour exposures in the range of 100 ppm; 23 workers exposed to 1.8 to 27 ppm complained of eye and throat irritation; mild bronchitis was common and irritant asthma developed in some of the workers; [ACGIH] Toxic to the liver in a chronic study of animals; [Desai, H. Phosphorus and Phosphorus Compounds. In: Sullivan J, Krieger G (eds).Hazardous Materials Toxicology.Baltimore:Williams & Wilkins,1992;939] A corrosive substance that can cause pulmonary edema; [ICSC] |
|---|
| Exposure Assessment |
|---|
| Skin Designation (ACGIH) |
No |
|---|
| TIH |
Yes |
|---|
| TLV (ACGIH) |
0.2 ppm |
|---|
| STEL (ACGIH) |
0.5 ppm |
|---|
| PEL (OSHA) |
0.5 ppm |
|---|
| MAK |
0.5 ppm |
|---|
| IDLH (NIOSH) |
25 ppm |
|---|
| Excerpts from Documentation for IDLHs |
Other animal data: Cats and guinea pigs exposed for 6 hours at 0.7 ppm showed only mild signs of intoxication and a 1�hour exposure at 2 to 4 ppm failed to produce severe signs of poisoning; however, a single 1�hour exposure at 50 to 90 ppm resulted in serious disturbances [Butjagin 1904]. . . . Human data: Workers exposed to concentrations ranging from 1.8 to 27 ppm had symptoms that included burning of the eyes and throat, irritation of the pharyngeal mucous membranes, and mild bronchitis within 2 to 6 hours after exposure [Sassi 1952]. |
|---|
| Vapor Pressure |
100 mm Hg |
|---|
| Lethal Concentration |
LC50 (rats) = 104 ppm/4 hr |
|---|
| Flammability (NFPA) |
0: will not burn |
|---|
| Adverse Effects |
|---|
| Toxic Pneumonitis |
Yes |
|---|
| Dermatotoxin |
Skin Burns |
|---|
| Hepatotoxin |
Hepatotoxin, Secondary |
|---|
| Nephrotoxin |
Yes |
|---|
| Links to Other NLM Databases |
|---|
| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: PHOSPHORUS TRICHLORIDE
|
|---|
|
|
