| Agent Name |
Phenylphosphine |
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| CAS Number |
638-21-1 |
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| Formula |
C6-H7-P |
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| Major Category |
Other Chemicals |
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| Synonyms |
Fenylfosfin; PF; Phosphaniline; [NIOSH] |
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| Category |
Phosphorus Compounds |
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| Description |
Clear, colorless liquid with a foul odor; [NIOSH] |
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| Sources/Uses |
Used as chemical intermediates; produced when phenylphosphinates are heated above 200 degrees C. [ACGIH] |
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| Comments |
A respiratory irritant with a repulsive odor; Phenylphosphine causes anemia and severe testicular degeneration in rats inhaling 2.2 ppm for 90 days. The acute toxicity of inhaled phenylphosphine is about 1/4 that of phosphine. Animals exposed to 2.2 ppm for 4 weeks have reversible hemolytic anemia. [ACGIH] A skin, eye, and respiratory tract irritant; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| Ceiling (ACGIH) |
0.05 ppm |
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| Vapor Pressure |
2.45 mm Hg |
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| Lethal Concentration |
LC50 (rats) = 38 ppm/4h |
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| Adverse Effects |
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| Anemia |
Anemia, Hemolytic |
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| Reproductive Toxin |
Yes |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: PHENYLPHOSPHINE
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