Skip Navigation

HazMap: Occupational Exposure to Hazardous Agents
HazMap Home SIS Home NLM Home

as Search Agents Search Diseases Search Jobs Full Text Search


Haz-Map Home on-tab Custom Search on-tab Help on-tab Web Glossary on-tab Reference on-tab
left corner Browse Haz-Map
right corner
Agent Name Iron pentacarbonyl
CAS Number 13463-40-6
Formula C5-Fe-O5
Major Category Toxic Gases & Vapors
Synonyms Iron carbonyl; Pentacarbonyl iron; [NIOSH]
Category Other Toxic Gases & Vapors
Description Colorless to yellow to dark-red, oily liquid; [NIOSH] Ignites in air; Insoluble in water; [Sullivan, p. 979]
Sources/Uses Used as an anti-knock agent in gasoline in Europe; may be generated when fine iron particles react with carbon monoxide; [ACGIH]
Comments Acute inhalation studies of animals: lung irritation and pulmonary edema are prominent toxic effects. [ACGIH] Also can cause liver,kidney, and CNS injury; [CAMEO] Readily absorbed through the skin; Acute exposure can injure the lungs (pneumonitis), liver, and kidneys. Chronic exposure can cause iron overload and hemochromatosis. [Sullivan, p. 982] See "ORGANOMETALS."
Exposure Assessment
Skin Designation (ACGIH) No
TIH Yes
Bioaccumulates Yes
TLV (ACGIH) 0.1 ppm
STEL (ACGIH) 0.2 ppm
MAK 0.1 ppm
Vapor Pressure 21 mm Hg
Explanatory Notes Flash point = 5 deg F; [CAMEO]
Reference Link International Chemical Safety Cards (WHO/IPCS/ILO)
Flammability (NFPA) 3: may ignite at ambient temperature
Adverse Effects
Toxic Pneumonitis Yes
Neurotoxin Other CNS Neurotoxin
Hepatotoxin Hepatotoxin, Secondary
Nephrotoxin Yes
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: IRON PENTACARBONYL  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:





Specialized Information Services   U.S. National Library of Medicine,
8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health
Privacy/Disclaimer Notice
Customer Service: tehip@teh.nlm.nih.gov
Last updated: September, 2008