| Agent Name |
Iodine |
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| CAS Number |
7553-56-2 |
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| Formula |
I2 |
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| Major Category |
Other Chemicals |
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| Synonyms |
Actomar; Diiodine; Eranol; Ethanolic solution of iodine; IODE [French]; Iodine; Iodine ((127)I2); Iodine Tincture USP; Iodine colloidal; Iodine crystals; Iodine solution; Iodine sublimed; Iodine tincture; Iodine-127; Iodio [Italian]; Iosan superdip; Jod [German, Polish]; Jood [Dutch]; Molecular iodine; Tincture iodine; Vistarin; [ChemIDplus] |
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| Category |
Elements, Nonmetallic |
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| Description |
Violet solid with a sharp, characteristic odor; [NIOSH] |
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| Sources/Uses |
Used as an antiseptic to kill bacteria, spores, viruses, and protozoa; Prepared as tinctures of 50% ethanol; Products that release iodine include iodoform, iodochlorhydroxyquin, povidone-iodine, and sodium and potassium iodides; Lugol's solution containing 5% iodine and 10% potassium iodide is used to treat hyperthyroidism and to prevent radioactive iodine absorption by the thyroid gland; Amiodarone is a cardiac drug that releases iodine and may cause thyrotoxicosis. Iodine is used in the production of dyes and photographic chemicals. [Olson, p. 227] Used in photography (reducing agent); [www.ci.tucson.az.us/arthazards/medium.html] |
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| Comments |
Iodine vapor is an irritant that may cause pneumonitis and pulmonary edema. Strong iodine tincture containing 7% iodine and 5% potassium iodide in 83% ethanol is corrosive to tissue. USP iodine tincture, povidone-iodine, and iodoforms are generally not corrosive. Ingestion of iodine can cause hemorrhagic gastroenteritis. The mean lethal dose is about 2-4 grams of free iodine. [Olson, p. 227] May cause respiratory tract irritation and pulmonary edema; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
0.01 ppm, inhalable fraction and vapor |
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| STEL (ACGIH) | , vapor and aerosol |
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| Ceiling (ACGIH) |
0.1 ppm |
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| PEL (OSHA) | Ceiling(OSHA) = 0.1 ppm |
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| IDLH (NIOSH) |
2 ppm |
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| Excerpts from Documentation for IDLHs |
Human data: It has been reported that work was difficult but possible at 0.15 to 0.2 ppm and that work was impossible at 0.3 ppm [Flury and Zernik 1931]. Exposures to 1 ppm have been reported to be highly irritating [Casarett 1975]. Eye irritation was experienced at 1.63 ppm after 2 minutes [ACGIH 1980]. |
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| Vapor Pressure |
0.3 mm Hg |
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| Lethal Concentration |
LCLo (rats) = 137 ppm/1H |
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| Explanatory Notes |
TLV is for "Iodine and iodides; [ACGIH] |
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| Adverse Effects |
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| Toxic Pneumonitis |
Yes |
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| Dermatotoxin |
Skin Burns |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: IODINE
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