| Agent Name |
Dimethylphthalate |
|---|
| CAS Number |
131-11-3 |
|---|
| Formula |
C10-H10-O4 |
|---|
| Major Category |
Plastics & Rubber |
|---|
| Synonyms |
1,2-Benzenedicarboxylic acid, dimethyl ester; Avolin; DMF (insect repellant); DMP; Dimethyl 1,2-benzenedicarboxylate; Dimethyl benzene-o-dicarboxylate; Dimethyl benzeneorthodicarboxylate; Dimethyl o-phthalate; Dimethyl phthalate; Dimethylester kyseliny ftalove [Czech]; Fermine; Mipax; NTM; Palatinol M; Phtalate de dimethyle [ISO-French]; Phthalic acid dimethyl ester; Phthalsaeuredimethylester [German]; Repeftal; Solvanom; Solvarone; Unimoll DM; [ChemIDplus] UN3082 |
|---|
| Category |
Phthalate Esters |
|---|
| Description |
Colorless, oily liquid with a slight, aromatic odor; Note: A solid below 42 degrees F; [NIOSH] |
|---|
| Sources/Uses |
Plasticizer (added to polymers to effect flexibility and/or toughness); also used as a solvent and insect repellant; [ACGIH] |
|---|
| Comments |
Ingestion can cause central nervous system depression. Used as a mosquito repellant during World War II, no skin sensitization was reported. DMP is a possible animal teratogen. [ACGIH] In high-dose reproductive studies of rats and mice, DEHP and other phthalates cause testicular damage to males and increased fetal losses and malformations to pregnant females. [Frazier, p. 350-2] The abstract to the article "Occupational contact dermatitis caused by computer mice" can be found in NIOSHTIC # 202472. One worker was patch test positive to dimethylphthalate and one to diethyl phthalate. [Reference #1] Not irritating to the skin based on human and animal information; [CHEMINFO] No listed effects of short-term or long-term exposure; [ICSC] |
|---|
| Restricted |
No longer registered for pesticide use; [HSDB] |
|---|
| Reference Link |
Occupational contact dermatitis caused by computer mice (No abstract available) |
|---|
| Exposure Assessment |
|---|
| Skin Designation (ACGIH) |
No |
|---|
| TLV (ACGIH) |
5 mg/m3 |
|---|
| PEL (OSHA) |
5 mg/m3 |
|---|
| IDLH (NIOSH) |
2000 mg/m3 |
|---|
| Excerpts from Documentation for IDLHs |
The revised IDLH for dimethylphthalate is 2,000 mg/m3 based on acute inhalation toxicity data in animals [Eller 1937]. [Note: Due to its low volatility, this concentration could only be reached at elevated temperatures or if the liquid droplets become airborne as in a mist.] |
|---|
| Vapor Pressure |
0.0031 mm Hg |
|---|
| Lethal Concentration |
LCLo (cats) = 9,630 mg/m3/6H |
|---|
| Explanatory Notes |
Flash point = 146 deg C; |
|---|
| Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
|---|
| Flammability (NFPA) |
1: must be preheated |
|---|
| Adverse Effects |
|---|
| Skin Sensitizer |
Yes |
|---|
| Reproductive Toxin |
Yes |
|---|
| Links to Other NLM Databases |
|---|
| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: DIMETHYLPHTHALATE
|
|---|
