| Agent Name |
Crotonaldehyde |
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| CAS Number |
4170-30-3 |
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| Formula |
C4-H6-O |
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| Major Category |
Toxic Gases & Vapors |
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| Synonyms |
1-Formylpropene; 2-Butenal; 2-Butenaldehyde; AI3-18303 (USDA); Crotonal; Crotonic aldehyde; Crotylaldehyde; Krotonaldehyd [Czech]; Methylpropenal; Propylene aldehyde; UN 1143; beta-Methylacrolein; [ChemIDplus] UN1143 |
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| Category |
Other Toxic Gases & Vapors |
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| Description |
Water-white liquid with a suffocating odor; Note: Turns pale-yellow on contact with air; [NIOSH] |
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| Sources/Uses |
Used in the synthesis of other organic chemicals; [ACGIH] |
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| Comments |
Rats exposed to 1500 ppm, a lethal concentration, develop pulmonary edema. [ACGIH] Liquid causes second degree burns after contact for a few minutes. [CHRIS] Also CAS # 123-73-9; A lachrymator; [CHEMINFO] Corrosive to the eyes; Can cause pulmonary edema; [ICSC] |
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| Reference Link |
ATSDR Medical Management - Crotonaldehyde |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Yes |
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| TIH |
Yes |
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| Ceiling (ACGIH) |
0.3 ppm |
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| PEL (OSHA) |
2 ppm |
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| IDLH (NIOSH) |
50 ppm |
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| Excerpts from Documentation for IDLHs |
Human data: Exposure to 4.1 ppm for 15 minutes was highly irritating to the nose and upper respiratory tract and produced lacrimation in 30 seconds [Sim and Pattle 1957]. In another study, exposures to 45 ppm proved very disagreeable after a few seconds, with conjunctival irritation evident [Rinehart 1967] |
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| Vapor Pressure |
30 mm Hg |
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| Odor Threshold Low |
0.06 ppm |
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| Odor Threshold High |
0.2 ppm |
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| RD50 |
3 ppm |
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| Lethal Concentration |
LC50 (rats) = 200 mg/m3/2H |
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| Explanatory Notes |
Detection odor threshold from AIHA (mean = 0.11 ppm); The Guide from the Emergency Response Guidebook is for "crotonaldehyde, inhibited." Flash point = 13 deg C; |
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| Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Toxic Pneumonitis |
Yes |
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| Dermatotoxin |
Skin Burns |
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| Lacrimator |
Yes |
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| IARC Carcinogen |
Not Classifiable |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: CROTONALDEHYDE
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