| Agent Name |
Carbon tetrabromide |
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| Alternative Name |
Tetrabromomethane |
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| CAS Number |
558-13-4 |
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| Formula |
C-Br4 |
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| Major Category |
Solvents |
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| Synonyms |
Carbon bromide; Methane tetrabromide; Tetrabromomethane; [NIOSH] UN2516 |
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| Category |
Brominated Solvents |
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| Description |
Colorless to yellow-brown crystals with a slight odor; [NIOSH] |
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| Sources/Uses |
Used in organic syntheses; [ACGIH] |
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| Comments |
In an acute study of mice, carbon tetrabromide was determined to be 2.2 times more toxic to the liver than carbon tetrachloride. It causes significant eye irritation (tearing) in workers even at lower exposure levels. [ACGIH] A lachrymator; [HSDB] Inhalation of high concentrations can cause CNS depression; Causes corrosive burns to eyes [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
0.1 ppm |
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| STEL (ACGIH) |
0.3 ppm |
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| Vapor Pressure |
0.72 mm Hg |
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| Half Life |
For bromide (depends on compound and route of administration) whole body: 1 hour to 12 days; [TDR, p. 214] |
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| Adverse Effects |
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| Dermatotoxin |
Skin Burns |
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| Lacrimator |
Yes |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Hepatotoxin |
Hepatotoxin, Primary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: TETRABROMOMETHANE
|
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