| Agent Name |
2-Aminopyridine |
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| CAS Number |
504-29-0 |
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| Formula |
C5-H6-N2 |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
2-Aminopyridine; alpha-Aminopyridine; 1,2-Dihydro-2-iminopyridine; 2-Aminopryidine; 2-Aminopyridine; 2-Pyridinamine; 2-Pyridylamine; Amino-2 pyridine; alpha-Aminopyridine; alpha-Pyridinamine; alpha-Pyridylamine; o-Aminopyridine; UN2671; [ChemIDplus] |
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| Category |
Pyridines |
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| Description |
White powder, leaflets, or crystals with a characteristic odor; [NIOSH] |
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| Sources/Uses |
Used to manufacture drugs and dyes; [Merck Index # 473] |
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| Comments |
A chemical plant worker died after a spill which contaminated his clothing. He did not remove his clothing, and symptoms began about 2 hours after the exposure with headache and dizziness followed by respiratory distress and convulsions. [ACGIH] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
0.5 ppm |
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| PEL (OSHA) |
0.5 ppm |
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| IDLH (NIOSH) |
5 ppm |
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| Excerpts from Documentation for IDLHs |
Very little quantitative data are available on which to base an IDLH for 2-aminopyridine. The chosen IDLH is based on the statement by ACGIH [1971] that a 5-hour exposure to about 5 ppm produced headache, increased blood pressure, and nausea in a worker [Watrous and Schulz 1950]. |
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| Vapor Pressure |
0.09 mm Hg |
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| Explanatory Notes |
Flash point = 198 deg F; [CAMEO] |
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| Adverse Effects |
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| Neurotoxin |
Other CNS Neurotoxin |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 2-AMINOPYRIDINE
|
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