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Agent Name bis-Chloromethyl ether
CAS Number 542-88-1
Formula C2-H4-Cl2-O
Major Category Other Chemicals
Synonyms 1,1'-Dichlorodimethyl ether; Chloro(chloromethoxy)methane; Chloromethyl ether; Dichlordimethylaether [German]; Dichloromethyl ether, symmetrical; Dimethyl-1,1'-dichloroether; Ether, bis(chloromethyl); Methane, oxybis(chloro-; Oxybis(chloromethane); sym-Dichloro-dimethyl ether; sym-Dichloromethyl ether; [ChemIDplus] UN2249
Category Other Chlorinated Hydrocarbons
Description Colorless liquid with a suffocating odor; [NIOSH]
Sources/Uses Used in the past to make polymers, resins, and textiles; Currently, only small amounts are used in enclosed systems in the chemical industry. [ACGIH]
Comments A corrosive substance that can cause pulmonary edema; [ICSC]
Restricted Regulated as a carcinogen; See 29CFR1910.1003;
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 0.001 ppm
Vapor Pressure 30 mm Hg
Lethal Concentration LC50 (rats) = 7 ppm/7h
Explanatory Notes Flash point < 19 deg C;
Half Life No reports found; [TDR, p. 191]
Reference Link ATSDR ToxFAQs - bis-Chloromethyl Ether
Flammability (NFPA) 3: may ignite at ambient temperature
Adverse Effects
Toxic Pneumonitis Yes
Lung Cancer Yes
Dermatotoxin Skin Burns
IARC Carcinogen Known Carcinogen
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: BIS(CHLOROMETHYL) ETHER  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:





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Last updated: September, 2008