| Agent Name |
Thiram |
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| CAS Number |
137-26-8 |
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| Formula |
C6-H12-N2-S4 |
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| Major Category |
Pesticides |
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| Synonyms |
Tetramethylthiuram disulfide; Thiuram; TMTD; TMT; TMTDS; Attack; Arasan; Aules; Fermide 850; Fernasan; FMC 2070; Hexathir; Mercuram; Micropearls; Nomersan; Pomarsol; Puralin; Rezifilm; Rhodiasan Express; Spotrete; Tersan; Thiosan; Thiotox; Thiramad; Thirame; Thiuramin; Thirasan; Tirampa; Tiuramyl; TMTC; TMTD 50 Borches; Trametan; Tuads; Tulisan |
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| Category |
Fungicides |
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| Description |
Colorless to yellow, crystalline solid with a characteristic odor. [Note: Commercial pesticide products may be dyed blue; [NIOSH] |
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| Sources/Uses |
Used as a crop fungicide and seed protectant; also used as an animal repellent to protect fruit trees and ornamentals; [EXTOXNET] |
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| Comments |
An irritant and a skin sensitizer, thiram is classified as "slightly toxic." [EXTOXNET] The EBCDCs (ethylenebisdithiocarbamates) can cause irritant and allergic contact dermatitis. EBDCs include ferbam, vapam, maneb, mancozeb, zineb, thiram, and ziram. They are also used as rubber accelerators. Ethylene thiourea (ETU), which may contaminate EBCDCs, is carcinogenic and teratogenic in animal experiments. [LaDou, p. 565-70] See the agent, "Ethylene thiourea." |
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| Reference Link |
EXTOXNET PIP - THIRAM |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
0.05 mg/m3, inhalable fraction and vapor |
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| PEL (OSHA) |
5 mg/m3 |
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| MAK |
1 mg/m3, inhalable fraction |
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| IDLH (NIOSH) |
100 mg/m3 |
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| Excerpts from Documentation for IDLHs |
Basis for revised IDLH: The revised IDLH for thiram is 100 mg/m3 based on acute inhalation toxicity data in animals [Marhold 1986]. This may be a conservative value due to the lack of relevant acute inhalation toxicity data for workers. |
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| Vapor Pressure |
8 x 10 -06 mm Hg |
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| Lethal Concentration |
LC50 (rats) = 500 mg/m3/4H |
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| Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
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| Adverse Effects |
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| Skin Sensitizer |
Yes |
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| IARC Carcinogen |
Not Classifiable |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: THIRAM
|
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