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Agent Name Halothane
CAS Number 151-67-7
Formula C2-H-Br-Cl-F3
Major Category Other Chemicals
Synonyms (+-)-2-Bromo-2-chloro-1,1,1-trifluoroethane; 1,1,1-Trifluoro-2-bromo-2-chloroethane; 1,1,1-Trifluoro-2-chloro-2-bromoethane; 1-Bromo-1-chloro-2,2,2-trifluoroethane; 2,2,2-Trifluoro-1-chloro-1-bromoethane; 2-Brom-2-chlor-1,1,1-trifluorethan; 2-Bromo-2-chloro-1,1,1-trifluoroethane; Alotano; Alotano [DCIT]; Anestan; Bromchlortrifluoraethanum; Bromochlorotrifluoroethane; Chalothane; Ethane, 1-bromo-1-chloro-2,2,2-trifluoro-; Ethane, 2-bromo-2-chloro-1,1,1-trifluoro-, (+-)-; Fluktan; Fluorotane; Fluothane; Freon 123B1; Ftorotan; Ftorotan [Russian]; Ftuorotan; Halan; Halotan; Halotano; Halotano [INN-Spanish]; Halothan; Halothane; Halothanum [INN-Latin]; Halsan; Narcotan; Narcotane; Narcotann NE-spofa [Russian]; Narkotan; Phthorothanum; Rhodialothan; [ChemIDplus] UN8027
Category Waste Anesthetic Gases
Description Clear, colorless liquid with a sweetish, pleasant odor; inhalation anesthetic; [NIOSH]
Sources/Uses Used as an anesthetic; [HSDB]
Comments See "WASTE ANESTHETIC GASES" Halothane is in the list of "Some volatile substances which may be abused by inhalation" published on the web site of the U.N. International Drug Control Programme, indicating its potential to cause narcosis in workers. [Reference #1] Inhalation of high concentrations can cause CNS depression, cardiac arrhythmias, and liver injury; [ICSC]
Reference Link Volatile Substance Abuse
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 50 ppm
MAK 5 ppm
Vapor Pressure 302 mm Hg
Lethal Concentration LC50 (rats) = 29,000 ppm
Explanatory Notes NIOSH Rel = 60 min. ceiling of 2 ppm;
Adverse Effects
Hepatotoxin Hepatotoxin, Secondary
Reproductive Toxin Yes
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Other InformationNo other related information on this agent was found.





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Last updated: September, 2008