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Agent Name Enflurane
CAS Number 13838-16-9
Formula C3-H2-Cl-F5-O
Major Category Other Uses
Synonyms (+-)-2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether; 2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether; 2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane; Anesthetic 347; Anesthetic Compound No. 347; C 347; Compound 347; Efrane; Enflurane; Enflurano [INN-Spanish]; Enfluranum [INN-Latin]; Ethane, 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-; Ethane, 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-, (+-)-; Ethrane; Methylflurether; OHIO 347; [ChemIDplus]
Category Waste Anesthetic Gases
Description Clear, colorless liquid with a mild, sweet odor; inhalation anesthetic; [NIOSH]
Sources/Uses Stable inhalation anesthetic; [ChemIDplus]
Comments See "WASTE ANESTHETIC GASES" Enflurane is in the list of "Some volatile substances which may be abused by inhalation" published on the web site of the U.N. International Drug Control Programme, indicating its potential to cause narcosis in workers. [Reference #1] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]
Reference Link Volatile Substance Abuse
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 75 ppm
MAK 20 ppm
Vapor Pressure 591 mm Hg
Lethal Concentration LC50 (rats) = 14,000 ppm/3h
Adverse Effects
Neurotoxin CNS Solvent Syndrome
Reproductive Toxin Yes
IARC Carcinogen Not Classifiable
Links to Other NLM Databases
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:





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Last updated: January, 2009