| Agent Name |
1-Butanethiol |
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| Alternative Name |
Butyl mercaptan |
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| CAS Number |
109-79-5 |
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| Formula |
C4-H10-S |
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| Major Category |
Other Chemicals |
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| Synonyms |
1-Mercaptobutane; Bear skunk; Butanethiol; Butyl mercaptan; Butylthiol; Normal butyl thioalcohol; Thiobutyl alcohol; n-Butanethiol; n-Butyl mercaptan; n-Butyl thioalcohol; n-Butylmercaptan; [ChemIDplus] UN2347 |
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| Category |
Thiols |
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| Description |
Colorless liquid with a strong, garlic-, cabbage-, or skunk-like odor; [NIOSH] |
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| Sources/Uses |
Used as a solvent, an odorant for natural gas, and an intermediate for insecticides and herbicides; [ACGIH] |
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| Comments |
In four hour inhalation studies, rats and mice show central nervous system depression. Oral and intraperitoneal doses at near lethal levels injure the liver and kidneys. Workers exposed in an accident to 50-500 ppm for one hour experienced weakness, sweating, headache, and vomiting. One of these workers lost unconscious for 20 minutes. [ACGIH] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
0.5 ppm |
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| PEL (OSHA) |
10 ppm |
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| MAK |
0.5 ppm |
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| IDLH (NIOSH) |
500 ppm |
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| Excerpts from Documentation for IDLHs |
Human data: Accidental exposure for 1 hour to an estimated concentration of 50 to 500 ppm has been reported to cause muscular weakness, malaise, sweating, nausea, vomiting, headache, and confusion [Gobbato and Terribile 1968]. |
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| Vapor Pressure |
45.5 mm Hg |
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| Odor Threshold Low |
0.00073 ppm |
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| Odor Threshold High |
0.001 ppm |
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| Lethal Concentration |
LC50 (rats) = 4,020 ppm/4H |
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| Explanatory Notes |
Detection odor threshold from AIHA (mean = 0.001 ppm); Flash point = 2 deg C; |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Reproductive Toxin |
Yes |
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| Other Poison |
Chemical Asphyxiant |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 1-BUTYL MERCAPTAN
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