| Agent Name |
Nitrogen tetroxide |
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| CAS Number |
10544-72-6 |
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| Formula |
N2-O4 |
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| Major Category |
Toxic Gases & Vapors |
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| Synonyms |
Dinitrogen tetroxide; Nitrogen oxide; Nitrogen oxide (N2O4); Nitrogen tetroxide; [ChemFinder] |
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| Category |
Oxidizers |
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| Description |
Colorless gas; [HSDB] |
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| Sources/Uses |
Exposure occurs where nitric acid is used, especially in acid baths for metal cleaning. Like NO2, it is also generated during welding operations. [HSDB] |
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| Comments |
Highly toxic; [Quick CPC] Like other nitrogen oxides, inhalation of NO4 may induce delayed pulmonary edema. Concentrations of 25-50 ppm cause irritation of the eyes and nose while 50-100 ppm can cause pulmonary edema and death. Cases of irritant-induced asthma have been reported. In animal experiments, methemoglobin level of 55% were produced in one hour after application of NO4 to the skin of rats. [HSDB] |
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| Reference Link |
HSDB |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| TIH |
Yes |
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| Vapor Pressure |
646 mm Hg |
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| Flammability (NFPA) |
0: will not burn |
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| Adverse Effects |
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| Toxic Pneumonitis |
Yes |
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| Methemoglobinemia |
Methemoglobinemia, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: NITROGEN TETROXIDE
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